In recent years, polyelectrolytes such as poly (diallyldimethylammonium chloride) and polystyrene sulfonate have been widely applied to hybrid thin films for industrial applications. In this paper, we report a method to modify the film by applying CO2 bubbles during layer-by-layer (LbL) assembly. The differences in thickness, mass, and surface morphology between CO2-treated hybrid LbL and pristine films were analyzed by quartz crystal microbalance, atomic force microscopy, scanning electron microscopy, and profilometry. The internal structure of the hybrid LbL films was investigated by analyzing the release of doxorubicin (DOX) incorporated in each film through photoluminescence. Upon CO2 treatment, the thickness, mass, and surface roughness increased, while the amount of incorporated DOX decreased.
Bibliographical noteFunding Information:
This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation of Korea (NRF) funded by the Korean Government (Grant 2012M3A9C6050104) and supported by the National Research Foundation of Korea (NRF), funded by the Korean Government Ministry of Science, ICT & Future Planning (Grant 2013R1A1A1076126). Additionally, this research was also supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (Grant HI14C-3266, HI15C-1653).
© 2016 Elsevier B.V.
All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Chemical Engineering(all)
- Industrial and Manufacturing Engineering