Effects of Korean black raspberry supplementation on oxidative stress and plasma antioxidant capacity in healthy male smokers

Eunkyo Park, Soo Muk Cho, Jung eun Lee, Seung Min Lee, Yesl Kim, Min Sun Go, Young Jae Kim, In Kyung Jung, Joong Hyuck Auh, Hyung Kyoon Choi, Jung Hyun Kim

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Oxidative stress has been implicated in the pathophysiology of chronic diseases and cigarette smoking is known to be one of the major sources of oxidants. In this study, we investigated whether Korean black raspberry (BR) supplementation could reduce smoke-induced oxidative stress in healthy male smokers. Thirty nine healthy male smokers received either 30 g of freeze-dried BR or placebo for four weeks. Anthropometric and dietary data, smoking history, blood lipid profiles, lipid peroxidation, DNA damage, and antioxidant enzyme activities were assessed at baseline and after supplementation. There was no difference of age, smoking history, anthropometry, and nutrient intake between groups. BR supplementation had no effect on plasma lipid profiles, LDL oxidation, and DNA damage. However, it significantly increased the activity of the antioxidant enzymes, glutathione peroxidase and catalase, and reduced plasma lipid peroxidation. In conclusion, BR supplementation may decrease cigarette smoke-induced oxidative stress through increase of endogenous antioxidant enzyme activities.

Original languageEnglish
Pages (from-to)393-402
Number of pages10
JournalJournal of Functional Foods
Volume16
DOIs
Publication statusPublished - 2015 Jun 1

All Science Journal Classification (ASJC) codes

  • Food Science
  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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    Park, E., Cho, S. M., Lee, J. E., Lee, S. M., Kim, Y., Go, M. S., Kim, Y. J., Jung, I. K., Auh, J. H., Choi, H. K., & Kim, J. H. (2015). Effects of Korean black raspberry supplementation on oxidative stress and plasma antioxidant capacity in healthy male smokers. Journal of Functional Foods, 16, 393-402. https://doi.org/10.1016/j.jff.2015.04.047