Efficacy of the fractional photothermolysis system with dynamic operating mode on acne scars and enlarged facial pores

Sung Bin Cho, JuHee Lee, Moon Jung Choi, Kyu Yeop Lee, SangHo Oh

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

BACKGROUND: Current treatments for acne scars and enlarged facial pores have shown limited efficacy. OBJECTIVE To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores. MATERIALS AND METHODS: Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar- and facial pore-treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores. RESULTS: Follow-up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post-treatment erythema, and edema, were resolved within 1 week. CONCLUSION: We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo-controlled, split-face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode.

Original languageEnglish
Pages (from-to)108-114
Number of pages7
JournalDermatologic Surgery
Volume35
Issue number1
DOIs
Publication statusPublished - 2009 Jan 1

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Acne Vulgaris
Cicatrix
Lasers
Therapeutics
Erythema
Edema
Placebos
Prospective Studies
Biopsy
Safety
Pain

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology

Cite this

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abstract = "BACKGROUND: Current treatments for acne scars and enlarged facial pores have shown limited efficacy. OBJECTIVE To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores. MATERIALS AND METHODS: Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar- and facial pore-treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores. RESULTS: Follow-up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51{\%} to 75{\%} and three demonstrated improvements of 76{\%} to 100{\%}, and for facial pores, five demonstrated moderate clinical improvements of 26{\%} to 50{\%} and three demonstrated improvements of 76{\%} to 100{\%}. Side effects, including pain, post-treatment erythema, and edema, were resolved within 1 week. CONCLUSION: We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo-controlled, split-face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode.",
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Efficacy of the fractional photothermolysis system with dynamic operating mode on acne scars and enlarged facial pores. / Cho, Sung Bin; Lee, JuHee; Choi, Moon Jung; Lee, Kyu Yeop; Oh, SangHo.

In: Dermatologic Surgery, Vol. 35, No. 1, 01.01.2009, p. 108-114.

Research output: Contribution to journalArticle

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