Abstract
(Chemical Equation Presented) An efficient solid-phase synthesis of trifunctional probes containing a photoreactive group, a reporter tag, and a carbohydrate ligand was developed. Labeling studies with these probes demonstrate that specific lectins can be labeled with high sensitivity and selectivity. This technique serves as a powerful tool for the rapid detection and profiling of lectins.
| Original language | English |
|---|---|
| Pages (from-to) | 5477-5480 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 7 |
| Issue number | 24 |
| DOIs | |
| Publication status | Published - 2005 Nov 24 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Lee, M. R., Jung, D. W., Williams, D., & Shin, I. (2005). Efficient solid-phase synthesis of trifunctional probes and their application to the detection of carbohydrate-binding proteins. Organic Letters, 7(24), 5477-5480. https://doi.org/10.1021/ol0523188