Efficient synthesis of epoxides from vicinal diols via cyclic sulfates

Doo Ok Jang, Yung Hyup Joo, Dae Hyan Cho

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Reaction of cyclic sulfates of vic-diols with sodium hydroxide in THF-MeOH produced the corresponding epoxides in excellent isolated yields at room temperature. Cyclic sulfates of trans-diols gave cis-epoxides, and cyclic sulfates of cis-diols afforded trans-epoxides exclusively. Various cyclic sulfates of vic-diols can be converted into the epoxides under the conditions.

Original languageEnglish
Pages (from-to)4489-4494
Number of pages6
JournalSynthetic Communications
Volume30
Issue number24
DOIs
Publication statusPublished - 2000 Jan 1

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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