Efficient synthesis of highly substituted indolizinones via iodocyclization and 1,2-shift

Jihyun Choi, Hyeong Lee Ge, Ikyon Kim

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The 5-endo-dig iodocyclization of propargylic alcohols followed by a 1,2-shift provided rapid access to 2-iodoindolizinones, while the 5-endo-trig iodocyclization of allylic alcohols and subsequent dehydroiodination and 1,2-shift led to indolizinones. A number of highly substituted indolizinones were constructed under these mild reaction conditions.

Original languageEnglish
Pages (from-to)1243-1249
Number of pages7
JournalSynlett
Issue number8
DOIs
Publication statusPublished - 2008 May 5

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Alcohols
allyl alcohol

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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Efficient synthesis of highly substituted indolizinones via iodocyclization and 1,2-shift. / Choi, Jihyun; Ge, Hyeong Lee; Kim, Ikyon.

In: Synlett, No. 8, 05.05.2008, p. 1243-1249.

Research output: Contribution to journalArticle

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