Efficient synthesis of macrocyclic paracyclophanes by ring-closing metathesis dimerization and trimerization reactions

Jinsung Tae, Young Keun Yang

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

(Matrix presented) Ring-closing metathesis reactions of para-disubstituted aromatic substrates produced macrocyclic [n.n]-, and [n.n.n]paracyclophanes efficiently through dimerization and trimerization reactions. Sufficiently long alkyl chains allowed direct monocyclizations to yield [n]paracyclophanes. A small library of paracyclophanes were generated by the combinatorial cross-metathesis approach.

Original languageEnglish
Pages (from-to)741-744
Number of pages4
JournalOrganic Letters
Volume5
Issue number5
DOIs
Publication statusPublished - 2003 Mar 6

Fingerprint

Dimerization
metathesis
closing
dimerization
Libraries
rings
Substrates
synthesis
matrices

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

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abstract = "(Matrix presented) Ring-closing metathesis reactions of para-disubstituted aromatic substrates produced macrocyclic [n.n]-, and [n.n.n]paracyclophanes efficiently through dimerization and trimerization reactions. Sufficiently long alkyl chains allowed direct monocyclizations to yield [n]paracyclophanes. A small library of paracyclophanes were generated by the combinatorial cross-metathesis approach.",
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Efficient synthesis of macrocyclic paracyclophanes by ring-closing metathesis dimerization and trimerization reactions. / Tae, Jinsung; Yang, Young Keun.

In: Organic Letters, Vol. 5, No. 5, 06.03.2003, p. 741-744.

Research output: Contribution to journalArticle

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AU - Yang, Young Keun

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