Electrically Driven Microengineered Bioinspired Soft Robots

Su Ryon Shin, Bianca Migliori, Beatrice Miccoli, Yi Chen Li, Pooria Mostafalu, Jungmok Seo, Serena Mandla, Alessandro Enrico, Silvia Antona, Ram Sabarish, Ting Zheng, Lorenzo Pirrami, Kaizhen Zhang, Yu Shrike Zhang, Kai Tak Wan, Danilo Demarchi, Mehmet R. Dokmeci, Ali Khademhosseini

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26 Citations (Scopus)

Abstract

To create life-like movements, living muscle actuator technologies have borrowed inspiration from biomimetic concepts in developing bioinspired robots. Here, the development of a bioinspired soft robotics system, with integrated self-actuating cardiac muscles on a hierarchically structured scaffold with flexible gold microelectrodes is reported. Inspired by the movement of living organisms, a batoid-fish-shaped substrate is designed and reported, which is composed of two micropatterned hydrogel layers. The first layer is a poly(ethylene glycol) hydrogel substrate, which provides a mechanically stable structure for the robot, followed by a layer of gelatin methacryloyl embedded with carbon nanotubes, which serves as a cell culture substrate, to create the actuation component for the soft body robot. In addition, flexible Au microelectrodes are embedded into the biomimetic scaffold, which not only enhance the mechanical integrity of the device, but also increase its electrical conductivity. After culturing and maturation of cardiomyocytes on the biomimetic scaffold, they show excellent myofiber organization and provide self-actuating motions aligned with the direction of the contractile force of the cells. The Au microelectrodes placed below the cell layer further provide localized electrical stimulation and control of the beating behavior of the bioinspired soft robot.

Original languageEnglish
Article number1704189
JournalAdvanced Materials
Volume30
Issue number10
DOIs
Publication statusPublished - 2018 Mar 8

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Shin, S. R., Migliori, B., Miccoli, B., Li, Y. C., Mostafalu, P., Seo, J., Mandla, S., Enrico, A., Antona, S., Sabarish, R., Zheng, T., Pirrami, L., Zhang, K., Zhang, Y. S., Wan, K. T., Demarchi, D., Dokmeci, M. R., & Khademhosseini, A. (2018). Electrically Driven Microengineered Bioinspired Soft Robots. Advanced Materials, 30(10), [1704189]. https://doi.org/10.1002/adma.201704189