Quantum-sized gold nanoclusters of size <2 nm possess unique and size-dependent redox behavior. Au25 nanoclusters (Au25NCs), in particular exhibit redox potentials closer to conventionally used mediators such as ferrocyanide and ferrocene and hence our objective was to utilize these clusters as mediators in the development of electrochemical sensors and biosensors. We have prepared modified electrodes containing Au25NCs and tested their electrocatalytic activity and amperometric sensing behavior. Au25NCs have behaved as an electronic conductor and redox mediator as well. Further, we have tuned the electrostatic charge on these clusters by using glutathione ligand and improved the selectivity of the modified electrode towards charged analytes. Finally, in order to examine the utility of the Au25NCs in electrochemical biosensing, an ionic liquid containing Au25NC has been prepared (Au25IL). The composite of Au25IL and glucose oxidase enzyme has exhibited to be an excellent biosensor towards the determination of glucose.
|Title of host publication||Chemical Sensors 12|
|Subtitle of host publication||Chemical and Biological Sensors and Analytical Systems|
|Editors||M. Carter, T. Yasukawa, B. A. Chin, A. L. Simonian, Y. Shimizu, W. Y. Lee, L. A. Nagahara, O. Niwa, R. Mukundan|
|Publisher||Electrochemical Society Inc.|
|Number of pages||8|
|Publication status||Published - 2016|
|Event||Symposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting - Honolulu, United States|
Duration: 2016 Oct 2 → 2016 Oct 7
|Other||Symposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting|
|Period||16/10/2 → 16/10/7|
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© The Electrochemical Society.
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