Electrochemical sensing using molecule-like gold nanoclusters

S. Senthil Kumar, Kyuju Kwak, Dongil Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Quantum-sized gold nanoclusters of size <2 nm possess unique and size-dependent redox behavior. Au25 nanoclusters (Au25NCs), in particular exhibit redox potentials closer to conventionally used mediators such as ferrocyanide and ferrocene and hence our objective was to utilize these clusters as mediators in the development of electrochemical sensors and biosensors. We have prepared modified electrodes containing Au25NCs and tested their electrocatalytic activity and amperometric sensing behavior. Au25NCs have behaved as an electronic conductor and redox mediator as well. Further, we have tuned the electrostatic charge on these clusters by using glutathione ligand and improved the selectivity of the modified electrode towards charged analytes. Finally, in order to examine the utility of the Au25NCs in electrochemical biosensing, an ionic liquid containing Au25NC has been prepared (Au25IL). The composite of Au25IL and glucose oxidase enzyme has exhibited to be an excellent biosensor towards the determination of glucose.

Original languageEnglish
Title of host publicationChemical Sensors 12
Subtitle of host publicationChemical and Biological Sensors and Analytical Systems
EditorsM. Carter, T. Yasukawa, B. A. Chin, A. L. Simonian, Y. Shimizu, W. Y. Lee, L. A. Nagahara, O. Niwa, R. Mukundan
PublisherElectrochemical Society Inc.
Pages131-138
Number of pages8
Edition16
ISBN (Electronic)9781607685395
DOIs
Publication statusPublished - 2016 Jan 1
EventSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting - Honolulu, United States
Duration: 2016 Oct 22016 Oct 7

Publication series

NameECS Transactions
Number16
Volume75
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Other

OtherSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting
CountryUnited States
CityHonolulu
Period16/10/216/10/7

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All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Kumar, S. S., Kwak, K., & Lee, D. (2016). Electrochemical sensing using molecule-like gold nanoclusters. In M. Carter, T. Yasukawa, B. A. Chin, A. L. Simonian, Y. Shimizu, W. Y. Lee, L. A. Nagahara, O. Niwa, & R. Mukundan (Eds.), Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems (16 ed., pp. 131-138). (ECS Transactions; Vol. 75, No. 16). Electrochemical Society Inc.. https://doi.org/10.1149/07516.0131ecst