Enantiodiscrimination using a chiral crown ether as a chiral solvating agent using NMR spectroscopy

Wonjae Lee, Eunjung Bang, Ji Hye Yun, Man Jeong Paik, Weontae Lee

Research output: Contribution to journalArticle

Abstract

For enantiomer separation of a variety of chiral compounds, a number of chiral selectors have been developed and applied. Among these chiral selectors are chiral crown ethers, a class of synthetic polyether molecules that bind protonated chiral primary amines with high selectivity. This article focuses on enantiodiscrimination using (18-crown-6)-2,3,11,12-tetracar-boxylic acid as a crown ether-type chiral solvating agent for nuclear magnetic resonance spectroscopic method in several chirotechnologies.

Original languageEnglish
JournalNatural product communications
Volume14
Issue number5
DOIs
Publication statusPublished - 2019 May

Fingerprint

Crown Ethers
nuclear magnetic resonance spectroscopy
ethers
Magnetic Resonance Spectroscopy
primary amines
enantiomers
Amines
Acids
acids
methodology
18-crown-6

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

Cite this

@article{628c41fecb914d3590afc5bfd204da17,
title = "Enantiodiscrimination using a chiral crown ether as a chiral solvating agent using NMR spectroscopy",
abstract = "For enantiomer separation of a variety of chiral compounds, a number of chiral selectors have been developed and applied. Among these chiral selectors are chiral crown ethers, a class of synthetic polyether molecules that bind protonated chiral primary amines with high selectivity. This article focuses on enantiodiscrimination using (18-crown-6)-2,3,11,12-tetracar-boxylic acid as a crown ether-type chiral solvating agent for nuclear magnetic resonance spectroscopic method in several chirotechnologies.",
author = "Wonjae Lee and Eunjung Bang and Yun, {Ji Hye} and Paik, {Man Jeong} and Weontae Lee",
year = "2019",
month = "5",
doi = "10.1177/1934578X19849191",
language = "English",
volume = "14",
journal = "Natural Product Communications",
issn = "1934-578X",
publisher = "Natural Product Communications",
number = "5",

}

Enantiodiscrimination using a chiral crown ether as a chiral solvating agent using NMR spectroscopy. / Lee, Wonjae; Bang, Eunjung; Yun, Ji Hye; Paik, Man Jeong; Lee, Weontae.

In: Natural product communications, Vol. 14, No. 5, 05.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Enantiodiscrimination using a chiral crown ether as a chiral solvating agent using NMR spectroscopy

AU - Lee, Wonjae

AU - Bang, Eunjung

AU - Yun, Ji Hye

AU - Paik, Man Jeong

AU - Lee, Weontae

PY - 2019/5

Y1 - 2019/5

N2 - For enantiomer separation of a variety of chiral compounds, a number of chiral selectors have been developed and applied. Among these chiral selectors are chiral crown ethers, a class of synthetic polyether molecules that bind protonated chiral primary amines with high selectivity. This article focuses on enantiodiscrimination using (18-crown-6)-2,3,11,12-tetracar-boxylic acid as a crown ether-type chiral solvating agent for nuclear magnetic resonance spectroscopic method in several chirotechnologies.

AB - For enantiomer separation of a variety of chiral compounds, a number of chiral selectors have been developed and applied. Among these chiral selectors are chiral crown ethers, a class of synthetic polyether molecules that bind protonated chiral primary amines with high selectivity. This article focuses on enantiodiscrimination using (18-crown-6)-2,3,11,12-tetracar-boxylic acid as a crown ether-type chiral solvating agent for nuclear magnetic resonance spectroscopic method in several chirotechnologies.

UR - http://www.scopus.com/inward/record.url?scp=85066401600&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066401600&partnerID=8YFLogxK

U2 - 10.1177/1934578X19849191

DO - 10.1177/1934578X19849191

M3 - Article

AN - SCOPUS:85066401600

VL - 14

JO - Natural Product Communications

JF - Natural Product Communications

SN - 1934-578X

IS - 5

ER -