Endoscopic injection sclerotherapy in patients with bleeding esophageal varices: a retrospective analysis.

J. B. Chung, D. K. Nam, KwangHyub Han, W. H. Kim, doyoung kim, C. Y. Chon, S. I. Lee, J. K. Kang, I. S. Park, H. J. Choi

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Abstract

Endoscopic injection sclerotherapy has been accepted as the procedure of choice for patients with variceal hemorrhage. To evaluate the efficiency of endoscopic injection sclerotherapy in patients with bleeding esophageal varices, we did a retrospective study of 52 patients (non-sclerotherapy group) with bleeding esophageal varices who were admitted to hospitals and did not receive sclerotherapy and of 50 patients (sclerotherapy group) who received sclerotherapy with ethanolamine oleate. The mortality (sclerotherapy group vs. non-sclerotherapy group: 18.0% vs. 32.7%) during index hospitalization, the bleeding risk factor (the number of rebleeds per patient/month; 1.56 +/- 2.76 vs. 4.96 +/- 9.99: mean +/- SEM) and the mortality due to bleeding (14.0% vs. 36.5%) were higher in the non-sclerotherapy group than in the sclerotherapy group. Only those in Child's class C who received sclerotherapy had a significantly better survival rate than the non-sclerotherapy group (p less than 0.05). Although formal comparisons were not made because of the retrospective nature of this study, endoscopic injection sclerotherapy is effective and appears to be superior to conventional medical treatments.

Original languageEnglish
Pages (from-to)5-14
Number of pages10
JournalThe Korean journal of internal medicine
Volume5
Issue number1
Publication statusPublished - 1990 Jan 1

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Sclerotherapy
Esophageal and Gastric Varices
Hemorrhage
Injections
Retrospective Studies
Mortality
Hospitalization
Survival Rate

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Chung, J. B. ; Nam, D. K. ; Han, KwangHyub ; Kim, W. H. ; kim, doyoung ; Chon, C. Y. ; Lee, S. I. ; Kang, J. K. ; Park, I. S. ; Choi, H. J. / Endoscopic injection sclerotherapy in patients with bleeding esophageal varices : a retrospective analysis. In: The Korean journal of internal medicine. 1990 ; Vol. 5, No. 1. pp. 5-14.
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Chung, JB, Nam, DK, Han, K, Kim, WH, kim, D, Chon, CY, Lee, SI, Kang, JK, Park, IS & Choi, HJ 1990, 'Endoscopic injection sclerotherapy in patients with bleeding esophageal varices: a retrospective analysis.', The Korean journal of internal medicine, vol. 5, no. 1, pp. 5-14.

Endoscopic injection sclerotherapy in patients with bleeding esophageal varices : a retrospective analysis. / Chung, J. B.; Nam, D. K.; Han, KwangHyub; Kim, W. H.; kim, doyoung; Chon, C. Y.; Lee, S. I.; Kang, J. K.; Park, I. S.; Choi, H. J.

In: The Korean journal of internal medicine, Vol. 5, No. 1, 01.01.1990, p. 5-14.

Research output: Contribution to journalArticle

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AU - Chung, J. B.

AU - Nam, D. K.

AU - Han, KwangHyub

AU - Kim, W. H.

AU - kim, doyoung

AU - Chon, C. Y.

AU - Lee, S. I.

AU - Kang, J. K.

AU - Park, I. S.

AU - Choi, H. J.

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N2 - Endoscopic injection sclerotherapy has been accepted as the procedure of choice for patients with variceal hemorrhage. To evaluate the efficiency of endoscopic injection sclerotherapy in patients with bleeding esophageal varices, we did a retrospective study of 52 patients (non-sclerotherapy group) with bleeding esophageal varices who were admitted to hospitals and did not receive sclerotherapy and of 50 patients (sclerotherapy group) who received sclerotherapy with ethanolamine oleate. The mortality (sclerotherapy group vs. non-sclerotherapy group: 18.0% vs. 32.7%) during index hospitalization, the bleeding risk factor (the number of rebleeds per patient/month; 1.56 +/- 2.76 vs. 4.96 +/- 9.99: mean +/- SEM) and the mortality due to bleeding (14.0% vs. 36.5%) were higher in the non-sclerotherapy group than in the sclerotherapy group. Only those in Child's class C who received sclerotherapy had a significantly better survival rate than the non-sclerotherapy group (p less than 0.05). Although formal comparisons were not made because of the retrospective nature of this study, endoscopic injection sclerotherapy is effective and appears to be superior to conventional medical treatments.

AB - Endoscopic injection sclerotherapy has been accepted as the procedure of choice for patients with variceal hemorrhage. To evaluate the efficiency of endoscopic injection sclerotherapy in patients with bleeding esophageal varices, we did a retrospective study of 52 patients (non-sclerotherapy group) with bleeding esophageal varices who were admitted to hospitals and did not receive sclerotherapy and of 50 patients (sclerotherapy group) who received sclerotherapy with ethanolamine oleate. The mortality (sclerotherapy group vs. non-sclerotherapy group: 18.0% vs. 32.7%) during index hospitalization, the bleeding risk factor (the number of rebleeds per patient/month; 1.56 +/- 2.76 vs. 4.96 +/- 9.99: mean +/- SEM) and the mortality due to bleeding (14.0% vs. 36.5%) were higher in the non-sclerotherapy group than in the sclerotherapy group. Only those in Child's class C who received sclerotherapy had a significantly better survival rate than the non-sclerotherapy group (p less than 0.05). Although formal comparisons were not made because of the retrospective nature of this study, endoscopic injection sclerotherapy is effective and appears to be superior to conventional medical treatments.

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