Endoscopic injection therapy

Sang Woon Kim, Yong Seung Lee, Sang Won Han

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Since the U.S. Food and Drug Administration approved dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of vesicoureteral reflux, endoscopic injection therapy using Deflux has become a popular alternative to open surgery and continuous antibiotic prophylaxis. Endoscopic correction with Deflux is minimally invasive, well tolerated, and provides cure rates approaching those of open surgery (i.e., approximately 80% in several studies). However, in recent years a less stringent approach to evaluating urinary tract infections (UTIs) and concerns about long-term efficacy and complications associated with endoscopic injection have limited the use of this therapy. In addition, there is little evidence supporting the efficacy of endoscopic injection therapy in preventing UTIs and vesicoureteral reflux-related renal scarring. In this report, we reviewed the current literature regarding endoscopic injection therapy and provided an updated overview of this topic.

Original languageEnglish
Pages (from-to)S38-S45
JournalInvestigative and clinical urology
Volume58
DOIs
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Urology

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