Endoscopic management of anastomotic leakage after gastrectomy for gastric cancer: How efficacious is it?

Yu Jin Kim, Sung Kwan Shin, Hyun Jung Lee, Hyun Soo Chung, Yong Chan Lee, Jun Chul Park, Woo Jin Hyung, Sung Hoon Noh, Choong Bae Kim, Sang Kil Lee

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Abstract

Background. Anastomotic leak is a dreadful complication with a high mortality rate. The authors aimed to evaluate the efficacy of endoscopic closure of anastomotic dehiscence after gastrectomy in patients with gastric cancer. Methods. The authors retrospectively reviewed 33 patients with anastomotic leakage who had underdone endoscopic treatment among 5249 patients with gastric cancer who underwent radical total or subtotal gastrectomy. Methods of endoscopic closure included clipping with or without detachable snare, fibrosealant, Histoacryl® or stent insertion. Results of endoscopic treatment were categorized as complete, partial closure and failure. Results. The size of the tissue defect was the only factor that had statistically significant differences among the cases with complete closure, partial closure and failure (p = 0.005). For tissue defects smaller than 2 cm in size, complete closure was achieved in 19 (73.1%), partial closure in 5 patients (19.2%) and 2 failed (7.6%). For those larger than 2 cm in size, one (14.3%) was completely closed, four (57.1%) were partially closed and two (28.6%) failed. Conclusions. Endoscopic treatment for anastomotic dehiscence smaller than 2 cm in size had excellent success rate in this study.

Original languageEnglish
Pages (from-to)111-118
Number of pages8
JournalScandinavian Journal of Gastroenterology
Volume48
Issue number1
DOIs
Publication statusPublished - 2013 Jan 1

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Anastomotic Leak
Gastrectomy
Stomach Neoplasms
Enbucrilate
Stents
Therapeutics
Mortality

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Kim, Yu Jin ; Shin, Sung Kwan ; Lee, Hyun Jung ; Chung, Hyun Soo ; Lee, Yong Chan ; Park, Jun Chul ; Hyung, Woo Jin ; Noh, Sung Hoon ; Kim, Choong Bae ; Lee, Sang Kil. / Endoscopic management of anastomotic leakage after gastrectomy for gastric cancer : How efficacious is it?. In: Scandinavian Journal of Gastroenterology. 2013 ; Vol. 48, No. 1. pp. 111-118.
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abstract = "Background. Anastomotic leak is a dreadful complication with a high mortality rate. The authors aimed to evaluate the efficacy of endoscopic closure of anastomotic dehiscence after gastrectomy in patients with gastric cancer. Methods. The authors retrospectively reviewed 33 patients with anastomotic leakage who had underdone endoscopic treatment among 5249 patients with gastric cancer who underwent radical total or subtotal gastrectomy. Methods of endoscopic closure included clipping with or without detachable snare, fibrosealant, Histoacryl{\circledR} or stent insertion. Results of endoscopic treatment were categorized as complete, partial closure and failure. Results. The size of the tissue defect was the only factor that had statistically significant differences among the cases with complete closure, partial closure and failure (p = 0.005). For tissue defects smaller than 2 cm in size, complete closure was achieved in 19 (73.1{\%}), partial closure in 5 patients (19.2{\%}) and 2 failed (7.6{\%}). For those larger than 2 cm in size, one (14.3{\%}) was completely closed, four (57.1{\%}) were partially closed and two (28.6{\%}) failed. Conclusions. Endoscopic treatment for anastomotic dehiscence smaller than 2 cm in size had excellent success rate in this study.",
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Endoscopic management of anastomotic leakage after gastrectomy for gastric cancer : How efficacious is it? / Kim, Yu Jin; Shin, Sung Kwan; Lee, Hyun Jung; Chung, Hyun Soo; Lee, Yong Chan; Park, Jun Chul; Hyung, Woo Jin; Noh, Sung Hoon; Kim, Choong Bae; Lee, Sang Kil.

In: Scandinavian Journal of Gastroenterology, Vol. 48, No. 1, 01.01.2013, p. 111-118.

Research output: Contribution to journalArticle

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AU - Lee, Sang Kil

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