Abstract
Background and Aim: Gastrointestinal carcinoid tumors <10mm in diameter and limited to the submucosal layer demonstrate a low frequency of lymph node and distant metastasis, and are suitable for endoscopic treatment. The aim of this study was to assess the efficacy, safety, and long-term prognosis of endoscopic resections for the treatment of duodenal carcinoid tumors. Methods: This study included a total of 41 duodenal carcinoid tumors in 38 patients between January 2006 and December 2011. The indications for endoscopic resection were lesions ≤10mm in diameter, confined to the submucosal layer, and without lymph node or distant metastasis. Endoscopic resection was accomplished using endoscopic mucosal resection (EMR), EMR with a ligation device (EMR-L), EMR after circumferential precutting, or endoscopic submucosal dissection (ESD). Results: EMR was performed in 18 tumors, EMR-L in 16, EMR after circumferential precutting in 3, and ESD in 4. En-bloc resection was performed in 39 tumors (95%), and endoscopic complete resection was achieved in 40 (98%); pathological complete resection was achieved in 17 tumors (41%). The endoscopic complete resection rate did not differ according to the resection method, but the pathological complete resection rate was higher for ESD than for EMR and EMR-L. Intraprocedural bleeding was noted in five cases, with no occurrence of perforation. Recurrence was not observed during the mean follow-up period of 17 months (range 1-53 months). Conclusion: Endoscopic resection appears to be a safe and effective treatment for duodenal carcinoid tumors measuring ≤10mm in diameter and confined to the submucosal layer.
| Original language | English |
|---|---|
| Pages (from-to) | 318-324 |
| Number of pages | 7 |
| Journal | Journal of Gastroenterology and Hepatology (Australia) |
| Volume | 29 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2014 Feb 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Hepatology
- Gastroenterology
Cite this
}
Endoscopic resection for duodenal carcinoid tumors : A multicenter, retrospective study. / Korean College of Helicobacter and Upper Gastrointestinal Research.
In: Journal of Gastroenterology and Hepatology (Australia), Vol. 29, No. 2, 01.02.2014, p. 318-324.Research output: Contribution to journal › Article
TY - JOUR
T1 - Endoscopic resection for duodenal carcinoid tumors
T2 - A multicenter, retrospective study
AU - Korean College of Helicobacter and Upper Gastrointestinal Research
AU - Kim, Gwang Ha
AU - Kim, Jin Il
AU - Jeon, Seong Woo
AU - Moon, Jeong Seop
AU - Chung, Il Kwun
AU - Jee, Sam Ryong
AU - Kim, Heung Up
AU - Seo, Geom Seog
AU - Baik, Gwang Ho
AU - Lee, Yong Chan
PY - 2014/2/1
Y1 - 2014/2/1
N2 - Background and Aim: Gastrointestinal carcinoid tumors <10mm in diameter and limited to the submucosal layer demonstrate a low frequency of lymph node and distant metastasis, and are suitable for endoscopic treatment. The aim of this study was to assess the efficacy, safety, and long-term prognosis of endoscopic resections for the treatment of duodenal carcinoid tumors. Methods: This study included a total of 41 duodenal carcinoid tumors in 38 patients between January 2006 and December 2011. The indications for endoscopic resection were lesions ≤10mm in diameter, confined to the submucosal layer, and without lymph node or distant metastasis. Endoscopic resection was accomplished using endoscopic mucosal resection (EMR), EMR with a ligation device (EMR-L), EMR after circumferential precutting, or endoscopic submucosal dissection (ESD). Results: EMR was performed in 18 tumors, EMR-L in 16, EMR after circumferential precutting in 3, and ESD in 4. En-bloc resection was performed in 39 tumors (95%), and endoscopic complete resection was achieved in 40 (98%); pathological complete resection was achieved in 17 tumors (41%). The endoscopic complete resection rate did not differ according to the resection method, but the pathological complete resection rate was higher for ESD than for EMR and EMR-L. Intraprocedural bleeding was noted in five cases, with no occurrence of perforation. Recurrence was not observed during the mean follow-up period of 17 months (range 1-53 months). Conclusion: Endoscopic resection appears to be a safe and effective treatment for duodenal carcinoid tumors measuring ≤10mm in diameter and confined to the submucosal layer.
AB - Background and Aim: Gastrointestinal carcinoid tumors <10mm in diameter and limited to the submucosal layer demonstrate a low frequency of lymph node and distant metastasis, and are suitable for endoscopic treatment. The aim of this study was to assess the efficacy, safety, and long-term prognosis of endoscopic resections for the treatment of duodenal carcinoid tumors. Methods: This study included a total of 41 duodenal carcinoid tumors in 38 patients between January 2006 and December 2011. The indications for endoscopic resection were lesions ≤10mm in diameter, confined to the submucosal layer, and without lymph node or distant metastasis. Endoscopic resection was accomplished using endoscopic mucosal resection (EMR), EMR with a ligation device (EMR-L), EMR after circumferential precutting, or endoscopic submucosal dissection (ESD). Results: EMR was performed in 18 tumors, EMR-L in 16, EMR after circumferential precutting in 3, and ESD in 4. En-bloc resection was performed in 39 tumors (95%), and endoscopic complete resection was achieved in 40 (98%); pathological complete resection was achieved in 17 tumors (41%). The endoscopic complete resection rate did not differ according to the resection method, but the pathological complete resection rate was higher for ESD than for EMR and EMR-L. Intraprocedural bleeding was noted in five cases, with no occurrence of perforation. Recurrence was not observed during the mean follow-up period of 17 months (range 1-53 months). Conclusion: Endoscopic resection appears to be a safe and effective treatment for duodenal carcinoid tumors measuring ≤10mm in diameter and confined to the submucosal layer.
UR - http://www.scopus.com/inward/record.url?scp=84907292629&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907292629&partnerID=8YFLogxK
U2 - 10.1111/jgh.12390
DO - 10.1111/jgh.12390
M3 - Article
C2 - 24117946
AN - SCOPUS:84907292629
VL - 29
SP - 318
EP - 324
JO - Journal of Gastroenterology and Hepatology (Australia)
JF - Journal of Gastroenterology and Hepatology (Australia)
SN - 0815-9319
IS - 2
ER -