Endovascular therapy combined with immunosuppressive treatment for pseudoaneurysms in patients with behçet's disease

Bon Kwon Koo, Won Heum Shim, Youngsup Yoon, Byoung Kwon Lee, Donghoon Choi, Yangsoo Jang, Do Yun Lee, Byung chul Chang

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Purpose: To evaluate the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppression for the treatment of arterial pseudoaneurysms due to Behçet's disease. Methods: Eleven pseudoaneurysms (3 in the abdominal aorta, 3 in the subclavian artery, and individual lesions in the brachiocephalic artery, renal artery, common iliac artery, common carotid artery, and the descending thoracic aorta) in 9 patients with Behçet's disease were treated with 10 stent-grafts and 1 self-expanding stent. All patients with elevated erythrocyte sedimentation rate (ESR) were treated with immunosuppressive agents (azathioprine, prednisolone) before and after the procedure. Results: Endovascular treatment was successful in all cases, without major adverse events. The ESR was reduced from 42.7±18.0 mm/h initially to 18.6±12.6 mm/h after immunosuppressive therapy prior to endovascular repair. During follow-up (mean 24.1±14.0 months, range 6-43), 8 of 11 lesions showed complete resolution. One stent-graft to treat a postsurgical recurrent carotid artery pseudoaneurysm was occluded, and an abdominal aortic pseudoaneurysm recurred; both patients stopped their medications. ESR during follow-up was 7.9±4.5 mm/h. Conclusions: Endovascular treatment for pseudoaneurysms due to Behçet's disease is feasible and effective when disease activity is strictly controlled with immunosuppressive therapy.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalJournal of Endovascular Therapy
Volume10
Issue number1
DOIs
Publication statusPublished - 2003 Feb 1

Fingerprint

False Aneurysm
Immunosuppressive Agents
Blood Sedimentation
Stents
Thoracic Aorta
Therapeutics
Carotid Artery Injuries
Transplants
Subclavian Artery
Iliac Artery
Common Carotid Artery
Abdominal Aorta
Azathioprine
Renal Artery
Prednisolone
Carotid Arteries
Immunosuppression
Arteries

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

@article{519a2a651d904b69af8bdff5c56cff87,
title = "Endovascular therapy combined with immunosuppressive treatment for pseudoaneurysms in patients with beh{\cc}et's disease",
abstract = "Purpose: To evaluate the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppression for the treatment of arterial pseudoaneurysms due to Beh{\cc}et's disease. Methods: Eleven pseudoaneurysms (3 in the abdominal aorta, 3 in the subclavian artery, and individual lesions in the brachiocephalic artery, renal artery, common iliac artery, common carotid artery, and the descending thoracic aorta) in 9 patients with Beh{\cc}et's disease were treated with 10 stent-grafts and 1 self-expanding stent. All patients with elevated erythrocyte sedimentation rate (ESR) were treated with immunosuppressive agents (azathioprine, prednisolone) before and after the procedure. Results: Endovascular treatment was successful in all cases, without major adverse events. The ESR was reduced from 42.7±18.0 mm/h initially to 18.6±12.6 mm/h after immunosuppressive therapy prior to endovascular repair. During follow-up (mean 24.1±14.0 months, range 6-43), 8 of 11 lesions showed complete resolution. One stent-graft to treat a postsurgical recurrent carotid artery pseudoaneurysm was occluded, and an abdominal aortic pseudoaneurysm recurred; both patients stopped their medications. ESR during follow-up was 7.9±4.5 mm/h. Conclusions: Endovascular treatment for pseudoaneurysms due to Beh{\cc}et's disease is feasible and effective when disease activity is strictly controlled with immunosuppressive therapy.",
author = "Koo, {Bon Kwon} and Shim, {Won Heum} and Youngsup Yoon and Lee, {Byoung Kwon} and Donghoon Choi and Yangsoo Jang and Lee, {Do Yun} and Chang, {Byung chul}",
year = "2003",
month = "2",
day = "1",
doi = "10.1583/1545-1550(2003)010<0075:ETCWIT>2.0.CO;2",
language = "English",
volume = "10",
pages = "75--80",
journal = "Journal of Endovascular Therapy",
issn = "1526-6028",
publisher = "International Society of Endovascular Specialists",
number = "1",

}

Endovascular therapy combined with immunosuppressive treatment for pseudoaneurysms in patients with behçet's disease. / Koo, Bon Kwon; Shim, Won Heum; Yoon, Youngsup; Lee, Byoung Kwon; Choi, Donghoon; Jang, Yangsoo; Lee, Do Yun; Chang, Byung chul.

In: Journal of Endovascular Therapy, Vol. 10, No. 1, 01.02.2003, p. 75-80.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Endovascular therapy combined with immunosuppressive treatment for pseudoaneurysms in patients with behçet's disease

AU - Koo, Bon Kwon

AU - Shim, Won Heum

AU - Yoon, Youngsup

AU - Lee, Byoung Kwon

AU - Choi, Donghoon

AU - Jang, Yangsoo

AU - Lee, Do Yun

AU - Chang, Byung chul

PY - 2003/2/1

Y1 - 2003/2/1

N2 - Purpose: To evaluate the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppression for the treatment of arterial pseudoaneurysms due to Behçet's disease. Methods: Eleven pseudoaneurysms (3 in the abdominal aorta, 3 in the subclavian artery, and individual lesions in the brachiocephalic artery, renal artery, common iliac artery, common carotid artery, and the descending thoracic aorta) in 9 patients with Behçet's disease were treated with 10 stent-grafts and 1 self-expanding stent. All patients with elevated erythrocyte sedimentation rate (ESR) were treated with immunosuppressive agents (azathioprine, prednisolone) before and after the procedure. Results: Endovascular treatment was successful in all cases, without major adverse events. The ESR was reduced from 42.7±18.0 mm/h initially to 18.6±12.6 mm/h after immunosuppressive therapy prior to endovascular repair. During follow-up (mean 24.1±14.0 months, range 6-43), 8 of 11 lesions showed complete resolution. One stent-graft to treat a postsurgical recurrent carotid artery pseudoaneurysm was occluded, and an abdominal aortic pseudoaneurysm recurred; both patients stopped their medications. ESR during follow-up was 7.9±4.5 mm/h. Conclusions: Endovascular treatment for pseudoaneurysms due to Behçet's disease is feasible and effective when disease activity is strictly controlled with immunosuppressive therapy.

AB - Purpose: To evaluate the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppression for the treatment of arterial pseudoaneurysms due to Behçet's disease. Methods: Eleven pseudoaneurysms (3 in the abdominal aorta, 3 in the subclavian artery, and individual lesions in the brachiocephalic artery, renal artery, common iliac artery, common carotid artery, and the descending thoracic aorta) in 9 patients with Behçet's disease were treated with 10 stent-grafts and 1 self-expanding stent. All patients with elevated erythrocyte sedimentation rate (ESR) were treated with immunosuppressive agents (azathioprine, prednisolone) before and after the procedure. Results: Endovascular treatment was successful in all cases, without major adverse events. The ESR was reduced from 42.7±18.0 mm/h initially to 18.6±12.6 mm/h after immunosuppressive therapy prior to endovascular repair. During follow-up (mean 24.1±14.0 months, range 6-43), 8 of 11 lesions showed complete resolution. One stent-graft to treat a postsurgical recurrent carotid artery pseudoaneurysm was occluded, and an abdominal aortic pseudoaneurysm recurred; both patients stopped their medications. ESR during follow-up was 7.9±4.5 mm/h. Conclusions: Endovascular treatment for pseudoaneurysms due to Behçet's disease is feasible and effective when disease activity is strictly controlled with immunosuppressive therapy.

UR - http://www.scopus.com/inward/record.url?scp=0038689379&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038689379&partnerID=8YFLogxK

U2 - 10.1583/1545-1550(2003)010<0075:ETCWIT>2.0.CO;2

DO - 10.1583/1545-1550(2003)010<0075:ETCWIT>2.0.CO;2

M3 - Article

C2 - 12751935

AN - SCOPUS:0038689379

VL - 10

SP - 75

EP - 80

JO - Journal of Endovascular Therapy

JF - Journal of Endovascular Therapy

SN - 1526-6028

IS - 1

ER -