Enhanced biolubrication on biomedical devices using hyaluronic acid-silica nanohybrid hydrogels

Changha Hwang, You Jin Min, Yun Jeong Seong, Dae Eun Kim, Hyoun Ee Kim, Seol Ha Jeong

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


In this work, highly lubricous hyaluronic acid-silica (HA-SiO2) nanohybrid coatings were fabricated through a sequential process consisting of a sol-gel followed by electrophoretic deposition (EPD). SiO2 nanoparticles were uniformly distributed in the coating layers, and the coating thickness was identified as approximately 1–2 μm regardless of the amount of SiO2. Incorporation of SiO2 into the HA polymer matrix enhanced the mechanical stability of the nanohybrid coatings, indicating greater interfacial bonding strength compared to HA coating layers alone. In addition, due to improved stability, the nanohybrid coatings showed excellent biolubrication properties, which were evaluated with a tribological experiment. These results indicate that the nanohybrid coatings have great potential to be used in biomedical applications that require superior biolubrication properties.

Original languageEnglish
Article number110503
JournalColloids and Surfaces B: Biointerfaces
Publication statusPublished - 2019 Dec 1

Bibliographical note

Funding Information:
This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) , funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI18C0493 ) Appendix A

Publisher Copyright:
© 2019

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry


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