Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance

Hojeong Yu, Kyujung Kim, Kyungjae Ma, Wonju Lee, Joung Woo Choi, Chae Ok Yun, Donghyun Kim

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

In this paper, we investigate localized surface plasmon resonance (SPR) detection based on nanoislands. Theoretical calculation performed with rigorous coupled-wave analysis and analytical transfer matrix method using effective medium theory suggests improvement on nanoislands in the limit of detection and sensitivity over conventional thin film-based SPR detection. Experimental results obtained with non-specific detection of ambient adenovirus confirm the improvement by more than one order of magnitude increase in the limit of detection. The enhancement achieved with nanoislands was explored in connection with efficient overlap between target and near-field distribution produced by nanoislands.

Original languageEnglish
Pages (from-to)249-255
Number of pages7
JournalBiosensors and Bioelectronics
Volume41
Issue number1
DOIs
Publication statusPublished - 2013 Mar 15

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Surface Plasmon Resonance
Surface plasmon resonance
Viruses
Virion
Limit of Detection
Transfer matrix method
Adenoviridae
Thin films

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

Cite this

Yu, Hojeong ; Kim, Kyujung ; Ma, Kyungjae ; Lee, Wonju ; Choi, Joung Woo ; Yun, Chae Ok ; Kim, Donghyun. / Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance. In: Biosensors and Bioelectronics. 2013 ; Vol. 41, No. 1. pp. 249-255.
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Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance. / Yu, Hojeong; Kim, Kyujung; Ma, Kyungjae; Lee, Wonju; Choi, Joung Woo; Yun, Chae Ok; Kim, Donghyun.

In: Biosensors and Bioelectronics, Vol. 41, No. 1, 15.03.2013, p. 249-255.

Research output: Contribution to journalArticle

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