An advanced optical activation of neural tissues is demonstrated using pulsed infrared light and plasmonic gold nanorods. Photothermal effect localized in plasma membrane triggers action potentials of in vivo neural tissues. Compared with conventional infrared stimulation, the suggested method can increase a neural responsivity and lower a threshold stimulation level significantly, thereby reducing a requisite radiant exposure and the concern of tissue damage.
Bibliographical noteFunding Information:
This work was supported by the Brain Korea 21 Plus Project, the Department of Electrical and Computer Engineering, Seoul National University in 2014 and by the Pioneer Research Center Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (NRF-2009-0082961 and Global Frontier Project (CISS-2013072261)). This work was also supported by the National Research Foundation of Korea (NRF) grants funded by the Korea government (MEST) (2011-0029485, 2011-0014529, 2012-0003809, NSF- 2013R1A1A1A05011990, and NSF-2014R1A1A1A05003770), the Public Welfare & Safety research program of the Ministry of Education, Science and Technology (NRF-2010-0020851) and the Technology Innovation Program (10033657) of the Ministry of Knowledge Economy (MKE).
All Science Journal Classification (ASJC) codes
- Materials Science(all)