Enhanced osteogenesis of human mesenchymal stem cells in PLGA scaffold by cyclic hydrostatic pressure

S. H. Kim, Y. H. Kim, Y. R. Choi, J. W. Shin, K. D. Park, J. W. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The possibility of human mesenchymal stem cells (MSC) to be grown and differentiated into osteoblast-like cells by cyclic pressure and fluid shear was investigated. Exposure of human MSCs to cyclic hydrostatic pressure daily for two weeks was found to enhance the osteogenic differentiation. There were significant differences in the DNA contents of the loaded and non-loaded hMSC-PLGA complex. Also, statistically significant differences in DNA content were found that DNA content was increased when human MSCs were exposed to hydrostatic pressure.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004 Dec 1
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period04/5/1704/5/21

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All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Kim, S. H., Kim, Y. H., Choi, Y. R., Shin, J. W., Park, K. D., & Lee, J. W. (2004). Enhanced osteogenesis of human mesenchymal stem cells in PLGA scaffold by cyclic hydrostatic pressure. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).