Enhancement of magnetic resonance contrast effect using ionic magnetic clusters

Sung Baek Seo, Jaemoon Yang, Tong Il Lee, Chan Hwa Chung, Yong Jin Song, Jin Suck Suh, Ho Geun Yoon, Yong Min Huh, Seungjoo Haam

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Precise diagnosis by magnetic resonance imaging (MRI) requires sensitive magnetic resonance probes to detect low concentrations of magnetic substances. Ionic magnetic clusters (IMCs) as versatile magnetic probes were successfully synthesized for enhancing the magnetic resonance (MR) contrast effect as well as ensuring high water solubility. IMCs with various sizes were prepared by assembly of MNCs using cationic cetyltrimethylammonium bromide (CTAB) and anionic sodium dodecyl sulfate (SDS). To synthesize IMCs in the aqueous phase, magnetic nanocrystals in an organic solvent were assembled with CTAB and SDS using the nanoemulsion method, to fabricate cationic magnetic clusters (CMCs) and anionic magnetic clusters (AMCs), respectively. IMCs demonstrated ultrasensitivity by MR imaging and sufficient magnetic mobility under an external magnetic field.

Original languageEnglish
Pages (from-to)429-434
Number of pages6
JournalJournal of Colloid and Interface Science
Volume319
Issue number2
DOIs
Publication statusPublished - 2008 Mar 15

Bibliographical note

Funding Information:
This work was supported by Korea Science and Engineering Foundation (KOSEF) (R15-2004-024-00000-0, No. M10755020001-07N5502-00110 and 2006-04649).

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry

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