The Analog mean delay (AMD) method is a multiphoton detection fluorescence lifetime measurement method. We have investigated the effect of the linearity of a photodetector response on the performance of the AMD method, which is a multiphoton detected fluorescence lifetime measurement method. A Monte-Carlo simulation scheme was adapted to generate various electronic signals for the AMD method with different linearity conditions of a photodetector. It is found that the photon economy is better if a photodetector with better linearity is used especially when the number of detected photons per pulse is low.
|Title of host publication||Multiphoton Microscopy in the Biomedical Sciences XVIII|
|Editors||Ammasi Periasamy, Xiaoliang S. Xie, Xiaoliang S. Xie, Karsten Konig, Peter T. C. So|
|Publication status||Published - 2018|
|Event||Multiphoton Microscopy in the Biomedical Sciences XVIII 2018 - San Francisco, United States|
Duration: 2018 Jan 28 → 2018 Jan 30
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Other||Multiphoton Microscopy in the Biomedical Sciences XVIII 2018|
|Period||18/1/28 → 18/1/30|
Bibliographical noteFunding Information:
This work was financially supported by the National Research Foundation of Korea (NRF-2013R1A1A2062448) through the Basic Science Research Program, Global Frontier Project (CAMM-2014M3A6B3063712), the Ministry of Science and ICT of Korea, Technology Innovation Program (10062417), and the Ministry of Trade, Industry and Energy of Korea.
© 2018 SPIE.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging