Environmental and Human Health Issues of Silver Nanoparticles Applications

Renat R. Khaydarov, Rashid A. Khaydarov, Svetlana Evgrafova, Stefanie Wagner, Seung Y. Cho

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)


The significant growth in applications of silver nanoparticles across -various branches of industry as well as in consumer products has caused concerns that nanosilver may have a toxic effect on the environment and human health and may have implications for eco-terorism. This paper presents research on antimicrobial effects of silver nanoparticles. We studied the cytotoxicity of silver nanoparticles via an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromid) assay that measures cell activity through the mitochondrial cleavage of a molecule that exhibits a change of colour that can be measured spectrophotometrically. NIH-3T3 (Swiss mouse embryo), HEP-G2 (human hepatocellular carcinoma), A-549 (human lung carcinoma), PC-12 (rat adrenal pheochromocytoma), and Colo-320 (human colon adenocarcinoma) cells were chosen in order to study different possible absorption paths of nanoparticles into the organism and various areas of particle accumulation in the body. The obtained MTT test results have shown that silver nanoparticles with concentrations of ∼1-10 ppm entering the body from air or liquid suspensions can present a potential risk to human health.

Original languageEnglish
Title of host publicationEnvironmental Security and Ecoterrorism
EditorsHami Alpas, Simon Berkowicz, Irina Ermakova
Number of pages11
Publication statusPublished - 2011

Publication series

NameNATO Science for Peace and Security Series C: Environmental Security
ISSN (Print)1874-6519

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)


Dive into the research topics of 'Environmental and Human Health Issues of Silver Nanoparticles Applications'. Together they form a unique fingerprint.

Cite this