Epidemiologic and clinical survey of Behçet's disease in Korea: The first multicenter study

Dongsik Bang, Ju Hee Lee, Eun So Lee, Sungnack Lee, Jong Soo Choi, Young Keun Kim, Baik Kee Cho, Jai Kyoung Koh, Young Ho Won, Nack In Kim, Seok Don Park, Hong Jun Ahn, Yoon Woo Lee, Han Young Wang, Won Woo Lee, Hee Chul Eun, Eun Sup Song, Sung Won Lee, Chang Woo Lee, Chong Ju LeeJae Ho Park, Yeong Wook Song, Sang Tae Kim, Chong Yeol Kim, Jang Kyu Park, Kyung Sool Kwon

Research output: Contribution to journalReview article

108 Citations (Scopus)

Abstract

The prevalence of Behçet's disease is the highest in the East Asian and the Mediterranean countries. Behçet's disease is also distributed in the Asian countries, but the nationwide survey has not been performed in Korea yet. The Korean Study Group for Behçet's Disease, founded in 1999, conducted a multicenter, retrospective survey on epidemiologic and clinical features of the patients with Behçet's disease from 20 hospitals around the nation from 1997 to 1999. Of 3,497 patients, 1,527 were classified into complete or incomplete type of Behçet's disease according to the revised Shimizu's classification. The sex ratio was 1:1.75 with the female predominance. Geographical distribution showed the highest frequency in Seoul (38.5%). Clinically, 98.8% had oral ulcers, 83.2% had genital ulcers, 84.3% had skin lesions and 50.9% had ocular lesions. As for the minor clinical manifestations, articular symptoms were the most frequent. The pathergy test showed positive in 15.4% of patients and revealed a higher positive rate in males (20.2%) than in females (12.7%). In conclusion, we performed the first multicenter study on Behçet's disease in Korea and revealed the female predominance, higher frequency of ocular lesions, and lower positivity of pathergy test in the patients.

Original languageEnglish
Pages (from-to)615-618
Number of pages4
JournalJournal of Korean medical science
Volume16
Issue number5
DOIs
Publication statusPublished - 2001 Oct

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Korea
Multicenter Studies
Oral Ulcer
Sex Ratio
Ulcer
Surveys and Questionnaires
Joints
Skin

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Bang, Dongsik ; Lee, Ju Hee ; Lee, Eun So ; Lee, Sungnack ; Choi, Jong Soo ; Kim, Young Keun ; Cho, Baik Kee ; Koh, Jai Kyoung ; Won, Young Ho ; Kim, Nack In ; Park, Seok Don ; Ahn, Hong Jun ; Lee, Yoon Woo ; Wang, Han Young ; Lee, Won Woo ; Eun, Hee Chul ; Song, Eun Sup ; Lee, Sung Won ; Lee, Chang Woo ; Lee, Chong Ju ; Park, Jae Ho ; Song, Yeong Wook ; Kim, Sang Tae ; Kim, Chong Yeol ; Park, Jang Kyu ; Kwon, Kyung Sool. / Epidemiologic and clinical survey of Behçet's disease in Korea : The first multicenter study. In: Journal of Korean medical science. 2001 ; Vol. 16, No. 5. pp. 615-618.
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title = "Epidemiologic and clinical survey of Beh{\cc}et's disease in Korea: The first multicenter study",
abstract = "The prevalence of Beh{\cc}et's disease is the highest in the East Asian and the Mediterranean countries. Beh{\cc}et's disease is also distributed in the Asian countries, but the nationwide survey has not been performed in Korea yet. The Korean Study Group for Beh{\cc}et's Disease, founded in 1999, conducted a multicenter, retrospective survey on epidemiologic and clinical features of the patients with Beh{\cc}et's disease from 20 hospitals around the nation from 1997 to 1999. Of 3,497 patients, 1,527 were classified into complete or incomplete type of Beh{\cc}et's disease according to the revised Shimizu's classification. The sex ratio was 1:1.75 with the female predominance. Geographical distribution showed the highest frequency in Seoul (38.5{\%}). Clinically, 98.8{\%} had oral ulcers, 83.2{\%} had genital ulcers, 84.3{\%} had skin lesions and 50.9{\%} had ocular lesions. As for the minor clinical manifestations, articular symptoms were the most frequent. The pathergy test showed positive in 15.4{\%} of patients and revealed a higher positive rate in males (20.2{\%}) than in females (12.7{\%}). In conclusion, we performed the first multicenter study on Beh{\cc}et's disease in Korea and revealed the female predominance, higher frequency of ocular lesions, and lower positivity of pathergy test in the patients.",
author = "Dongsik Bang and Lee, {Ju Hee} and Lee, {Eun So} and Sungnack Lee and Choi, {Jong Soo} and Kim, {Young Keun} and Cho, {Baik Kee} and Koh, {Jai Kyoung} and Won, {Young Ho} and Kim, {Nack In} and Park, {Seok Don} and Ahn, {Hong Jun} and Lee, {Yoon Woo} and Wang, {Han Young} and Lee, {Won Woo} and Eun, {Hee Chul} and Song, {Eun Sup} and Lee, {Sung Won} and Lee, {Chang Woo} and Lee, {Chong Ju} and Park, {Jae Ho} and Song, {Yeong Wook} and Kim, {Sang Tae} and Kim, {Chong Yeol} and Park, {Jang Kyu} and Kwon, {Kyung Sool}",
year = "2001",
month = "10",
doi = "10.3346/jkms.2001.16.5.615",
language = "English",
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pages = "615--618",
journal = "Journal of Korean Medical Science",
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Bang, D, Lee, JH, Lee, ES, Lee, S, Choi, JS, Kim, YK, Cho, BK, Koh, JK, Won, YH, Kim, NI, Park, SD, Ahn, HJ, Lee, YW, Wang, HY, Lee, WW, Eun, HC, Song, ES, Lee, SW, Lee, CW, Lee, CJ, Park, JH, Song, YW, Kim, ST, Kim, CY, Park, JK & Kwon, KS 2001, 'Epidemiologic and clinical survey of Behçet's disease in Korea: The first multicenter study', Journal of Korean medical science, vol. 16, no. 5, pp. 615-618. https://doi.org/10.3346/jkms.2001.16.5.615

Epidemiologic and clinical survey of Behçet's disease in Korea : The first multicenter study. / Bang, Dongsik; Lee, Ju Hee; Lee, Eun So; Lee, Sungnack; Choi, Jong Soo; Kim, Young Keun; Cho, Baik Kee; Koh, Jai Kyoung; Won, Young Ho; Kim, Nack In; Park, Seok Don; Ahn, Hong Jun; Lee, Yoon Woo; Wang, Han Young; Lee, Won Woo; Eun, Hee Chul; Song, Eun Sup; Lee, Sung Won; Lee, Chang Woo; Lee, Chong Ju; Park, Jae Ho; Song, Yeong Wook; Kim, Sang Tae; Kim, Chong Yeol; Park, Jang Kyu; Kwon, Kyung Sool.

In: Journal of Korean medical science, Vol. 16, No. 5, 10.2001, p. 615-618.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Epidemiologic and clinical survey of Behçet's disease in Korea

T2 - The first multicenter study

AU - Bang, Dongsik

AU - Lee, Ju Hee

AU - Lee, Eun So

AU - Lee, Sungnack

AU - Choi, Jong Soo

AU - Kim, Young Keun

AU - Cho, Baik Kee

AU - Koh, Jai Kyoung

AU - Won, Young Ho

AU - Kim, Nack In

AU - Park, Seok Don

AU - Ahn, Hong Jun

AU - Lee, Yoon Woo

AU - Wang, Han Young

AU - Lee, Won Woo

AU - Eun, Hee Chul

AU - Song, Eun Sup

AU - Lee, Sung Won

AU - Lee, Chang Woo

AU - Lee, Chong Ju

AU - Park, Jae Ho

AU - Song, Yeong Wook

AU - Kim, Sang Tae

AU - Kim, Chong Yeol

AU - Park, Jang Kyu

AU - Kwon, Kyung Sool

PY - 2001/10

Y1 - 2001/10

N2 - The prevalence of Behçet's disease is the highest in the East Asian and the Mediterranean countries. Behçet's disease is also distributed in the Asian countries, but the nationwide survey has not been performed in Korea yet. The Korean Study Group for Behçet's Disease, founded in 1999, conducted a multicenter, retrospective survey on epidemiologic and clinical features of the patients with Behçet's disease from 20 hospitals around the nation from 1997 to 1999. Of 3,497 patients, 1,527 were classified into complete or incomplete type of Behçet's disease according to the revised Shimizu's classification. The sex ratio was 1:1.75 with the female predominance. Geographical distribution showed the highest frequency in Seoul (38.5%). Clinically, 98.8% had oral ulcers, 83.2% had genital ulcers, 84.3% had skin lesions and 50.9% had ocular lesions. As for the minor clinical manifestations, articular symptoms were the most frequent. The pathergy test showed positive in 15.4% of patients and revealed a higher positive rate in males (20.2%) than in females (12.7%). In conclusion, we performed the first multicenter study on Behçet's disease in Korea and revealed the female predominance, higher frequency of ocular lesions, and lower positivity of pathergy test in the patients.

AB - The prevalence of Behçet's disease is the highest in the East Asian and the Mediterranean countries. Behçet's disease is also distributed in the Asian countries, but the nationwide survey has not been performed in Korea yet. The Korean Study Group for Behçet's Disease, founded in 1999, conducted a multicenter, retrospective survey on epidemiologic and clinical features of the patients with Behçet's disease from 20 hospitals around the nation from 1997 to 1999. Of 3,497 patients, 1,527 were classified into complete or incomplete type of Behçet's disease according to the revised Shimizu's classification. The sex ratio was 1:1.75 with the female predominance. Geographical distribution showed the highest frequency in Seoul (38.5%). Clinically, 98.8% had oral ulcers, 83.2% had genital ulcers, 84.3% had skin lesions and 50.9% had ocular lesions. As for the minor clinical manifestations, articular symptoms were the most frequent. The pathergy test showed positive in 15.4% of patients and revealed a higher positive rate in males (20.2%) than in females (12.7%). In conclusion, we performed the first multicenter study on Behçet's disease in Korea and revealed the female predominance, higher frequency of ocular lesions, and lower positivity of pathergy test in the patients.

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U2 - 10.3346/jkms.2001.16.5.615

DO - 10.3346/jkms.2001.16.5.615

M3 - Review article

C2 - 11641532

AN - SCOPUS:0035488263

VL - 16

SP - 615

EP - 618

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 5

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