Epidemiologic and clinical survey of Behçet's disease in Korea: The first multicenter study

Dongsik Bang, Ju Hee Lee, Eun So Lee, Sungnack Lee, Jong Soo Choi, Young Keun Kim, Baik Kee Cho, Jai Kyoung Koh, Young Ho Won, Nack In Kim, Seok Don Park, Hong Jun Ahn, Yoon Woo Lee, Han Young Wang, Won Woo Lee, Hee Chul Eun, Eun Sup Song, Sung Won Lee, Chang Woo Lee, Chong Ju LeeJae Ho Park, Yeong Wook Song, Sang Tae Kim, Chong Yeol Kim, Jang Kyu Park, Kyung Sool Kwon

Research output: Contribution to journalReview articlepeer-review

109 Citations (Scopus)

Abstract

The prevalence of Behçet's disease is the highest in the East Asian and the Mediterranean countries. Behçet's disease is also distributed in the Asian countries, but the nationwide survey has not been performed in Korea yet. The Korean Study Group for Behçet's Disease, founded in 1999, conducted a multicenter, retrospective survey on epidemiologic and clinical features of the patients with Behçet's disease from 20 hospitals around the nation from 1997 to 1999. Of 3,497 patients, 1,527 were classified into complete or incomplete type of Behçet's disease according to the revised Shimizu's classification. The sex ratio was 1:1.75 with the female predominance. Geographical distribution showed the highest frequency in Seoul (38.5%). Clinically, 98.8% had oral ulcers, 83.2% had genital ulcers, 84.3% had skin lesions and 50.9% had ocular lesions. As for the minor clinical manifestations, articular symptoms were the most frequent. The pathergy test showed positive in 15.4% of patients and revealed a higher positive rate in males (20.2%) than in females (12.7%). In conclusion, we performed the first multicenter study on Behçet's disease in Korea and revealed the female predominance, higher frequency of ocular lesions, and lower positivity of pathergy test in the patients.

Original languageEnglish
Pages (from-to)615-618
Number of pages4
JournalJournal of Korean medical science
Volume16
Issue number5
DOIs
Publication statusPublished - 2001 Oct

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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