Epidemiology of deep cutaneous fungal infections in Korea (2006-2010)

Myoung Shin Kim, Jae Kyung Kim, Mi Woo Lee, Kee Chan Moon, Beom Joon Kim, Sang Wook Son, Hyo Hyun Ahn, SangHo Oh, Hee Joon Yu, Dong Youn Lee, Kwang Hyun Cho, Baik Kee Cho, Moon Bum Kim, Kee Suck Suh, You Chan Kim, Byung In Ro, Joon Soo Park, Jong Soo Choi, Jee Bum Lee

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Deep cutaneous fungal infections (DCFI) occur worldwide and their prevalence is influenced by personal factors of the affected patients and the geographic and cultural features. Surveillance studies of DCFI with respect to the various clinical backgrounds of affected patients can ultimately help to improve their outcome. Expanding on our previous study, we performed a retrospective analysis of patients with DCFI who were treated in a group of university teaching hospitals in Korea to determine the trends within a 5-year period. A retrospective medical record review of patients with DCFI treated between 2006 and 2010 at 16 university teaching hospitals located throughout Korea was performed. Among the 51 cases of DCFI (median patient age, 47.0 years), opportunistic infections in immunocompromised hosts accounted for half. Patients in this group included 11 who were transplant recipients and 12 with malignancies. Overall, Candida (13/51) was the most common causative organism, followed by Sporothrix (12) and Aspergillus (6). Papuloplaques and nodular lesions were the typical presentation, with maculopatches and ulcers also occurring in considerable numbers. Ten patients had systemic involvement. Eight immunocompromised patients did not recover from the disease despite systemic antifungal treatment. Our results highlight the equal involvement of opportunistic and primary pathogens in DCFI, as determined in cases from a 5-year period. Especially in immunocompromised hosts with non-specific skin findings, clinical suspicion is important because failure to diagnose a DCFI causes significant morbidity and possibly even death.

Original languageEnglish
Pages (from-to)962-966
Number of pages5
JournalJournal of Dermatology
Volume42
Issue number10
DOIs
Publication statusPublished - 2015 Oct 1

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Mycoses
Korea
Epidemiology
Skin
Immunocompromised Host
Teaching Hospitals
Sporothrix
Opportunistic Infections
Aspergillus
Candida
Ulcer
Medical Records
Morbidity

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Kim, M. S., Kim, J. K., Lee, M. W., Moon, K. C., Kim, B. J., Son, S. W., ... Lee, J. B. (2015). Epidemiology of deep cutaneous fungal infections in Korea (2006-2010). Journal of Dermatology, 42(10), 962-966. https://doi.org/10.1111/1346-8138.12968
Kim, Myoung Shin ; Kim, Jae Kyung ; Lee, Mi Woo ; Moon, Kee Chan ; Kim, Beom Joon ; Son, Sang Wook ; Ahn, Hyo Hyun ; Oh, SangHo ; Yu, Hee Joon ; Lee, Dong Youn ; Cho, Kwang Hyun ; Cho, Baik Kee ; Kim, Moon Bum ; Suh, Kee Suck ; Kim, You Chan ; Ro, Byung In ; Park, Joon Soo ; Choi, Jong Soo ; Lee, Jee Bum. / Epidemiology of deep cutaneous fungal infections in Korea (2006-2010). In: Journal of Dermatology. 2015 ; Vol. 42, No. 10. pp. 962-966.
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abstract = "Deep cutaneous fungal infections (DCFI) occur worldwide and their prevalence is influenced by personal factors of the affected patients and the geographic and cultural features. Surveillance studies of DCFI with respect to the various clinical backgrounds of affected patients can ultimately help to improve their outcome. Expanding on our previous study, we performed a retrospective analysis of patients with DCFI who were treated in a group of university teaching hospitals in Korea to determine the trends within a 5-year period. A retrospective medical record review of patients with DCFI treated between 2006 and 2010 at 16 university teaching hospitals located throughout Korea was performed. Among the 51 cases of DCFI (median patient age, 47.0 years), opportunistic infections in immunocompromised hosts accounted for half. Patients in this group included 11 who were transplant recipients and 12 with malignancies. Overall, Candida (13/51) was the most common causative organism, followed by Sporothrix (12) and Aspergillus (6). Papuloplaques and nodular lesions were the typical presentation, with maculopatches and ulcers also occurring in considerable numbers. Ten patients had systemic involvement. Eight immunocompromised patients did not recover from the disease despite systemic antifungal treatment. Our results highlight the equal involvement of opportunistic and primary pathogens in DCFI, as determined in cases from a 5-year period. Especially in immunocompromised hosts with non-specific skin findings, clinical suspicion is important because failure to diagnose a DCFI causes significant morbidity and possibly even death.",
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Kim, MS, Kim, JK, Lee, MW, Moon, KC, Kim, BJ, Son, SW, Ahn, HH, Oh, S, Yu, HJ, Lee, DY, Cho, KH, Cho, BK, Kim, MB, Suh, KS, Kim, YC, Ro, BI, Park, JS, Choi, JS & Lee, JB 2015, 'Epidemiology of deep cutaneous fungal infections in Korea (2006-2010)', Journal of Dermatology, vol. 42, no. 10, pp. 962-966. https://doi.org/10.1111/1346-8138.12968

Epidemiology of deep cutaneous fungal infections in Korea (2006-2010). / Kim, Myoung Shin; Kim, Jae Kyung; Lee, Mi Woo; Moon, Kee Chan; Kim, Beom Joon; Son, Sang Wook; Ahn, Hyo Hyun; Oh, SangHo; Yu, Hee Joon; Lee, Dong Youn; Cho, Kwang Hyun; Cho, Baik Kee; Kim, Moon Bum; Suh, Kee Suck; Kim, You Chan; Ro, Byung In; Park, Joon Soo; Choi, Jong Soo; Lee, Jee Bum.

In: Journal of Dermatology, Vol. 42, No. 10, 01.10.2015, p. 962-966.

Research output: Contribution to journalReview article

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T1 - Epidemiology of deep cutaneous fungal infections in Korea (2006-2010)

AU - Kim, Myoung Shin

AU - Kim, Jae Kyung

AU - Lee, Mi Woo

AU - Moon, Kee Chan

AU - Kim, Beom Joon

AU - Son, Sang Wook

AU - Ahn, Hyo Hyun

AU - Oh, SangHo

AU - Yu, Hee Joon

AU - Lee, Dong Youn

AU - Cho, Kwang Hyun

AU - Cho, Baik Kee

AU - Kim, Moon Bum

AU - Suh, Kee Suck

AU - Kim, You Chan

AU - Ro, Byung In

AU - Park, Joon Soo

AU - Choi, Jong Soo

AU - Lee, Jee Bum

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Deep cutaneous fungal infections (DCFI) occur worldwide and their prevalence is influenced by personal factors of the affected patients and the geographic and cultural features. Surveillance studies of DCFI with respect to the various clinical backgrounds of affected patients can ultimately help to improve their outcome. Expanding on our previous study, we performed a retrospective analysis of patients with DCFI who were treated in a group of university teaching hospitals in Korea to determine the trends within a 5-year period. A retrospective medical record review of patients with DCFI treated between 2006 and 2010 at 16 university teaching hospitals located throughout Korea was performed. Among the 51 cases of DCFI (median patient age, 47.0 years), opportunistic infections in immunocompromised hosts accounted for half. Patients in this group included 11 who were transplant recipients and 12 with malignancies. Overall, Candida (13/51) was the most common causative organism, followed by Sporothrix (12) and Aspergillus (6). Papuloplaques and nodular lesions were the typical presentation, with maculopatches and ulcers also occurring in considerable numbers. Ten patients had systemic involvement. Eight immunocompromised patients did not recover from the disease despite systemic antifungal treatment. Our results highlight the equal involvement of opportunistic and primary pathogens in DCFI, as determined in cases from a 5-year period. Especially in immunocompromised hosts with non-specific skin findings, clinical suspicion is important because failure to diagnose a DCFI causes significant morbidity and possibly even death.

AB - Deep cutaneous fungal infections (DCFI) occur worldwide and their prevalence is influenced by personal factors of the affected patients and the geographic and cultural features. Surveillance studies of DCFI with respect to the various clinical backgrounds of affected patients can ultimately help to improve their outcome. Expanding on our previous study, we performed a retrospective analysis of patients with DCFI who were treated in a group of university teaching hospitals in Korea to determine the trends within a 5-year period. A retrospective medical record review of patients with DCFI treated between 2006 and 2010 at 16 university teaching hospitals located throughout Korea was performed. Among the 51 cases of DCFI (median patient age, 47.0 years), opportunistic infections in immunocompromised hosts accounted for half. Patients in this group included 11 who were transplant recipients and 12 with malignancies. Overall, Candida (13/51) was the most common causative organism, followed by Sporothrix (12) and Aspergillus (6). Papuloplaques and nodular lesions were the typical presentation, with maculopatches and ulcers also occurring in considerable numbers. Ten patients had systemic involvement. Eight immunocompromised patients did not recover from the disease despite systemic antifungal treatment. Our results highlight the equal involvement of opportunistic and primary pathogens in DCFI, as determined in cases from a 5-year period. Especially in immunocompromised hosts with non-specific skin findings, clinical suspicion is important because failure to diagnose a DCFI causes significant morbidity and possibly even death.

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