Abstract
BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. This observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.
| Original language | English |
|---|---|
| Pages (from-to) | 839-842 |
| Number of pages | 4 |
| Journal | IFMBE Proceedings |
| Volume | 16 |
| Issue number | 1 |
| Publication status | Published - 2007 Jan 1 |
| Event | 11th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2007 - Ljubljana, Slovenia Duration: 2007 Jun 26 → 2007 Jun 30 |
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All Science Journal Classification (ASJC) codes
- Bioengineering
- Biomedical Engineering
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Estimation method for brain activities are influenced by blood pulsation effect. / Lee, W. H.; Ku, Jeong Hun; Lee, H. R.; Han, K. W.; Park, J. S.; Kim, Jae-Jin; Kim, I. Y.; Kim, S. I.
In: IFMBE Proceedings, Vol. 16, No. 1, 01.01.2007, p. 839-842.Research output: Contribution to journal › Conference article
TY - JOUR
T1 - Estimation method for brain activities are influenced by blood pulsation effect
AU - Lee, W. H.
AU - Ku, Jeong Hun
AU - Lee, H. R.
AU - Han, K. W.
AU - Park, J. S.
AU - Kim, Jae-Jin
AU - Kim, I. Y.
AU - Kim, S. I.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. This observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.
AB - BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. This observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.
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M3 - Conference article
AN - SCOPUS:85007106878
VL - 16
SP - 839
EP - 842
JO - IFMBE Proceedings
JF - IFMBE Proceedings
SN - 1680-0737
IS - 1
ER -