EuroSCORE as a Predictor of Death and Myocardial Infarction After Unprotected Left Main Coronary Stenting

Young Hak Kim, Jung Min Ahn, Duk Woo Park, Bong Ki Lee, Cheol Whan Lee, Myeongki Hong, Jae Joong Kim, Seong Wook Park, Seung Jung Park

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

This study aimed to identify the independent predictors of death and myocardial infarction (MI) after unprotected left main coronary artery stenting with bare metal (n = 148) or sirolimus-eluting (n = 176) stents between January 2000 and March 2005. To identify independent predictors of death and nonfatal MI, all available parameters were evaluated. Systemic surgical risk stratification systems such as the EuroSCORE and Parsonnet score were included in the analysis. Clinical information at 9 months was available in 98% of patients (median follow-up 26.3 months). During this period, death/MI occurred in 42 patients (13%). Of the 5 deaths, 4 were related to cardiac and 1 to noncardiac causes. By multivariate Cox regression analysis, a high EuroSCORE (≥6; hazard ratio 3.4, 95% confidence interval 1.2 to 9.6, p = 0.023), number of stents used (hazard ratio 1.8, 95% confidence interval 1.0 to 3.1, p = 0.042), and treatment with a glycoprotein IIb/IIIa inhibitor (hazard ratio 8.6, 95% confidence interval 2.7 to 27.4, p <0.001) were independent predictors of death/MI. Areas under the receiver-operating characteristic curve of EuroSCORE and number of stents were 0.61 (95% confidence interval 0.52 to 0.70, p = 0.023) and 0.61 (95% confidence interval 0.51 to 0.70, p = 0.028), respectively. In conclusion, high surgical risk estimated by systemic risk stratification of the EuroSCORE appears to be associated with unfavorable outcomes of unprotected left main coronary artery stenting.

Original languageEnglish
Pages (from-to)1567-1570
Number of pages4
JournalAmerican Journal of Cardiology
Volume98
Issue number12
DOIs
Publication statusPublished - 2006 Dec 15

Fingerprint

Myocardial Infarction
Confidence Intervals
Stents
Coronary Vessels
Platelet Glycoprotein GPIIb-IIIa Complex
Sirolimus
ROC Curve
Metals
Regression Analysis
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Kim, Young Hak ; Ahn, Jung Min ; Park, Duk Woo ; Lee, Bong Ki ; Lee, Cheol Whan ; Hong, Myeongki ; Kim, Jae Joong ; Park, Seong Wook ; Park, Seung Jung. / EuroSCORE as a Predictor of Death and Myocardial Infarction After Unprotected Left Main Coronary Stenting. In: American Journal of Cardiology. 2006 ; Vol. 98, No. 12. pp. 1567-1570.
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abstract = "This study aimed to identify the independent predictors of death and myocardial infarction (MI) after unprotected left main coronary artery stenting with bare metal (n = 148) or sirolimus-eluting (n = 176) stents between January 2000 and March 2005. To identify independent predictors of death and nonfatal MI, all available parameters were evaluated. Systemic surgical risk stratification systems such as the EuroSCORE and Parsonnet score were included in the analysis. Clinical information at 9 months was available in 98{\%} of patients (median follow-up 26.3 months). During this period, death/MI occurred in 42 patients (13{\%}). Of the 5 deaths, 4 were related to cardiac and 1 to noncardiac causes. By multivariate Cox regression analysis, a high EuroSCORE (≥6; hazard ratio 3.4, 95{\%} confidence interval 1.2 to 9.6, p = 0.023), number of stents used (hazard ratio 1.8, 95{\%} confidence interval 1.0 to 3.1, p = 0.042), and treatment with a glycoprotein IIb/IIIa inhibitor (hazard ratio 8.6, 95{\%} confidence interval 2.7 to 27.4, p <0.001) were independent predictors of death/MI. Areas under the receiver-operating characteristic curve of EuroSCORE and number of stents were 0.61 (95{\%} confidence interval 0.52 to 0.70, p = 0.023) and 0.61 (95{\%} confidence interval 0.51 to 0.70, p = 0.028), respectively. In conclusion, high surgical risk estimated by systemic risk stratification of the EuroSCORE appears to be associated with unfavorable outcomes of unprotected left main coronary artery stenting.",
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EuroSCORE as a Predictor of Death and Myocardial Infarction After Unprotected Left Main Coronary Stenting. / Kim, Young Hak; Ahn, Jung Min; Park, Duk Woo; Lee, Bong Ki; Lee, Cheol Whan; Hong, Myeongki; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.

In: American Journal of Cardiology, Vol. 98, No. 12, 15.12.2006, p. 1567-1570.

Research output: Contribution to journalArticle

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N2 - This study aimed to identify the independent predictors of death and myocardial infarction (MI) after unprotected left main coronary artery stenting with bare metal (n = 148) or sirolimus-eluting (n = 176) stents between January 2000 and March 2005. To identify independent predictors of death and nonfatal MI, all available parameters were evaluated. Systemic surgical risk stratification systems such as the EuroSCORE and Parsonnet score were included in the analysis. Clinical information at 9 months was available in 98% of patients (median follow-up 26.3 months). During this period, death/MI occurred in 42 patients (13%). Of the 5 deaths, 4 were related to cardiac and 1 to noncardiac causes. By multivariate Cox regression analysis, a high EuroSCORE (≥6; hazard ratio 3.4, 95% confidence interval 1.2 to 9.6, p = 0.023), number of stents used (hazard ratio 1.8, 95% confidence interval 1.0 to 3.1, p = 0.042), and treatment with a glycoprotein IIb/IIIa inhibitor (hazard ratio 8.6, 95% confidence interval 2.7 to 27.4, p <0.001) were independent predictors of death/MI. Areas under the receiver-operating characteristic curve of EuroSCORE and number of stents were 0.61 (95% confidence interval 0.52 to 0.70, p = 0.023) and 0.61 (95% confidence interval 0.51 to 0.70, p = 0.028), respectively. In conclusion, high surgical risk estimated by systemic risk stratification of the EuroSCORE appears to be associated with unfavorable outcomes of unprotected left main coronary artery stenting.

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