Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure

I. Han, J. H. Choi, Hong Koo Baik, Jongchul Park, J. K. Kim, K. Y. Lee, S. M. Chung, I. S. Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.

Original languageEnglish
Pages (from-to)425-428
Number of pages4
JournalKey Engineering Materials
Volume288-289
Publication statusPublished - 2005 Dec 1

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Atmospheric pressure
Acids
Scaffolds
Oxygen
Scaffolds (biology)
Tissue engineering
Hydroxyl Radical
Ether
Surface properties
Wetting
Ethers
Flow rate
Fluxes
Milk
polylactic acid-polyglycolic acid copolymer
Polymers

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Han, I. ; Choi, J. H. ; Baik, Hong Koo ; Park, Jongchul ; Kim, J. K. ; Lee, K. Y. ; Chung, S. M. ; Lee, I. S. / Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure. In: Key Engineering Materials. 2005 ; Vol. 288-289. pp. 425-428.
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Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure. / Han, I.; Choi, J. H.; Baik, Hong Koo; Park, Jongchul; Kim, J. K.; Lee, K. Y.; Chung, S. M.; Lee, I. S.

In: Key Engineering Materials, Vol. 288-289, 01.12.2005, p. 425-428.

Research output: Contribution to journalArticle

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AB - The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.

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