Evidence that the ratio of donor kidney weight to recipient body weight, donor age, and episodes of acute rejection correlate independently with live-donor graft function

YuSeun Kim, Myoung Soo Kim, Dae Suk Han, Dong Kee Kim, Sung Min Myoung, Soon Il Kim, Kiil Park

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background. We demonstrated that higher donor kidney weight-to-recipient body weight (KW/BW) ratio showed better graft function in acute rejection-free renal recipients. Methods. We investigated the impacts of KW/BW ratios on the graft function including acute rejection and donor's age in 259 live-donor renal recipients. Renal parameters were measured yearly. Correlations between the variables and each parameter were assessed by mixed regression and analysis of variance. Results. Renal function showed a positive correlation with the KW/BW ratio, but an inverse correlation with the rejection episodes and donor's age. The regression slope for serum creatinine or creatinine clearance by these covariants was consistent each year. On comparing the lower KW/BW ratios (<3.0) with higher ratios (≥4.5), the higher was associated with better graft function. Increased donor's age was associated with worse graft function. Conclusions. KW/BW ratio, donor's age, and the number of acute rejections are independent covariants for graft function.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalTransplantation
Volume74
Issue number2
DOIs
Publication statusPublished - 2002 Jul 27

Fingerprint

Body Weight
Transplants
Kidney
Weights and Measures
Creatinine
Analysis of Variance
Regression Analysis
Serum

All Science Journal Classification (ASJC) codes

  • Transplantation

Cite this

Kim, YuSeun ; Soo Kim, Myoung ; Suk Han, Dae ; Kee Kim, Dong ; Min Myoung, Sung ; Il Kim, Soon ; Park, Kiil. / Evidence that the ratio of donor kidney weight to recipient body weight, donor age, and episodes of acute rejection correlate independently with live-donor graft function. In: Transplantation. 2002 ; Vol. 74, No. 2. pp. 280-283.
@article{9823a5aba0494fa0a15072f8b48c2334,
title = "Evidence that the ratio of donor kidney weight to recipient body weight, donor age, and episodes of acute rejection correlate independently with live-donor graft function",
abstract = "Background. We demonstrated that higher donor kidney weight-to-recipient body weight (KW/BW) ratio showed better graft function in acute rejection-free renal recipients. Methods. We investigated the impacts of KW/BW ratios on the graft function including acute rejection and donor's age in 259 live-donor renal recipients. Renal parameters were measured yearly. Correlations between the variables and each parameter were assessed by mixed regression and analysis of variance. Results. Renal function showed a positive correlation with the KW/BW ratio, but an inverse correlation with the rejection episodes and donor's age. The regression slope for serum creatinine or creatinine clearance by these covariants was consistent each year. On comparing the lower KW/BW ratios (<3.0) with higher ratios (≥4.5), the higher was associated with better graft function. Increased donor's age was associated with worse graft function. Conclusions. KW/BW ratio, donor's age, and the number of acute rejections are independent covariants for graft function.",
author = "YuSeun Kim and {Soo Kim}, Myoung and {Suk Han}, Dae and {Kee Kim}, Dong and {Min Myoung}, Sung and {Il Kim}, Soon and Kiil Park",
year = "2002",
month = "7",
day = "27",
doi = "10.1097/00007890-200207270-00021",
language = "English",
volume = "74",
pages = "280--283",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

Evidence that the ratio of donor kidney weight to recipient body weight, donor age, and episodes of acute rejection correlate independently with live-donor graft function. / Kim, YuSeun; Soo Kim, Myoung; Suk Han, Dae; Kee Kim, Dong; Min Myoung, Sung; Il Kim, Soon; Park, Kiil.

In: Transplantation, Vol. 74, No. 2, 27.07.2002, p. 280-283.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Evidence that the ratio of donor kidney weight to recipient body weight, donor age, and episodes of acute rejection correlate independently with live-donor graft function

AU - Kim, YuSeun

AU - Soo Kim, Myoung

AU - Suk Han, Dae

AU - Kee Kim, Dong

AU - Min Myoung, Sung

AU - Il Kim, Soon

AU - Park, Kiil

PY - 2002/7/27

Y1 - 2002/7/27

N2 - Background. We demonstrated that higher donor kidney weight-to-recipient body weight (KW/BW) ratio showed better graft function in acute rejection-free renal recipients. Methods. We investigated the impacts of KW/BW ratios on the graft function including acute rejection and donor's age in 259 live-donor renal recipients. Renal parameters were measured yearly. Correlations between the variables and each parameter were assessed by mixed regression and analysis of variance. Results. Renal function showed a positive correlation with the KW/BW ratio, but an inverse correlation with the rejection episodes and donor's age. The regression slope for serum creatinine or creatinine clearance by these covariants was consistent each year. On comparing the lower KW/BW ratios (<3.0) with higher ratios (≥4.5), the higher was associated with better graft function. Increased donor's age was associated with worse graft function. Conclusions. KW/BW ratio, donor's age, and the number of acute rejections are independent covariants for graft function.

AB - Background. We demonstrated that higher donor kidney weight-to-recipient body weight (KW/BW) ratio showed better graft function in acute rejection-free renal recipients. Methods. We investigated the impacts of KW/BW ratios on the graft function including acute rejection and donor's age in 259 live-donor renal recipients. Renal parameters were measured yearly. Correlations between the variables and each parameter were assessed by mixed regression and analysis of variance. Results. Renal function showed a positive correlation with the KW/BW ratio, but an inverse correlation with the rejection episodes and donor's age. The regression slope for serum creatinine or creatinine clearance by these covariants was consistent each year. On comparing the lower KW/BW ratios (<3.0) with higher ratios (≥4.5), the higher was associated with better graft function. Increased donor's age was associated with worse graft function. Conclusions. KW/BW ratio, donor's age, and the number of acute rejections are independent covariants for graft function.

UR - http://www.scopus.com/inward/record.url?scp=0037183198&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037183198&partnerID=8YFLogxK

U2 - 10.1097/00007890-200207270-00021

DO - 10.1097/00007890-200207270-00021

M3 - Article

C2 - 12151743

AN - SCOPUS:0037183198

VL - 74

SP - 280

EP - 283

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 2

ER -