Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK

Jae Hwan Lee, R. Doyle Stulting, Dong Ho Lee, Christopher Seungkyu Lee, Woon Cho Kim, Eung Kweon Kim

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalJournal of Refractive Surgery
Volume24
Issue number1
Publication statusPublished - 2008 Jan 1

Fingerprint

Lasers
Corneal Opacity
Myopia
Mitomycin
DNA Sequence Analysis
Confocal Microscopy
Visual Acuity
Corneal dystrophy Avellino type

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology

Cite this

Lee, J. H., Stulting, R. D., Lee, D. H., Lee, C. S., Kim, W. C., & Kim, E. K. (2008). Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK. Journal of Refractive Surgery, 24(1), 39-45.
Lee, Jae Hwan ; Stulting, R. Doyle ; Lee, Dong Ho ; Lee, Christopher Seungkyu ; Kim, Woon Cho ; Kim, Eung Kweon. / Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK. In: Journal of Refractive Surgery. 2008 ; Vol. 24, No. 1. pp. 39-45.
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Lee, JH, Stulting, RD, Lee, DH, Lee, CS, Kim, WC & Kim, EK 2008, 'Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK', Journal of Refractive Surgery, vol. 24, no. 1, pp. 39-45.

Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK. / Lee, Jae Hwan; Stulting, R. Doyle; Lee, Dong Ho; Lee, Christopher Seungkyu; Kim, Woon Cho; Kim, Eung Kweon.

In: Journal of Refractive Surgery, Vol. 24, No. 1, 01.01.2008, p. 39-45.

Research output: Contribution to journalArticle

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AB - PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.

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