TY - JOUR
T1 - Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK
AU - Lee, Jae Hwan
AU - Stulting, R. Doyle
AU - Lee, Dong Ho
AU - Lee, Christopher Seungkyu
AU - Kim, Woon Cho
AU - Kim, Eung Kweon
PY - 2008/1
Y1 - 2008/1
N2 - PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.
AB - PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.
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U2 - 10.3928/1081597x-20080101-06
DO - 10.3928/1081597x-20080101-06
M3 - Article
C2 - 18269147
AN - SCOPUS:38349153891
VL - 24
SP - 39
EP - 45
JO - Journal of Refractive Surgery
JF - Journal of Refractive Surgery
SN - 1081-597X
IS - 1
ER -