Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK

Jae Hwan Lee; R. Doyle Stulting; Dong Ho Lee; Christopher Seungkyu Lee; Woon Cho Kim; Eung Kweon Kim

doi:10.3928/1081597x-20080101-06

Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK

Jae Hwan Lee, R. Doyle Stulting, Dong Ho Lee, Christopher Seungkyu Lee, Woon Cho Kim, Eung Kweon Kim

Department of Ophthalmology

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.

Original language	English
Pages (from-to)	39-45
Number of pages	7
Journal	Journal of Refractive Surgery
Volume	24
Issue number	1
DOIs	https://doi.org/10.3928/1081597x-20080101-06
Publication status	Published - 2008 Jan

All Science Journal Classification (ASJC) codes

Surgery
Ophthalmology

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title = "Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK",

abstract = "PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.",

author = "Lee, {Jae Hwan} and Stulting, {R. Doyle} and Lee, {Dong Ho} and Lee, {Christopher Seungkyu} and Kim, {Woon Cho} and Kim, {Eung Kweon}",

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T1 - Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK

AU - Lee, Jae Hwan

AU - Stulting, R. Doyle

AU - Lee, Dong Ho

AU - Lee, Christopher Seungkyu

AU - Kim, Woon Cho

AU - Kim, Eung Kweon

PY - 2008/1

Y1 - 2008/1

N2 - PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.

AB - PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients. CONCLUSIONS: LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.

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