Abstract
Porokeratosis is a heterogeneous group of disorders that are mostly inherited in an autosomal dominant fashion. It has a wide variety of clinical manifestations with a characteristic histological finding of cornoid lamella. Porokeratosis usually affects the trunk or the extremities. Exclusive facial lesions are rare, although 15% of patients with disseminated, superficial, actinic porokeratosis do have facial lesions. Herein, we discuss the case of a 25-year-old woman who noticed the appearance of well-defined, brownish, macular lesions located on both cheeks. She had no other symptoms. A skin examination showed well-demarcated, multiple, brownish macules with raised hyperkeratotic borders on both cheeks and a half-palm-sized, arcuate-shaped lesion formed by grouped macules on the right cheek. No other parts of the body were affected. Histopathological examination of a biopsy specimen obtained from the hyperkeratotic margin gave a diagnosis of porokeratosis with follicular involvement of the cornoid lamellae. Topical pimecrolimus was applied twice a day to the lesions, although little improvement was achieved after 2 months.
| Original language | English |
|---|---|
| Pages (from-to) | 1072-1075 |
| Number of pages | 4 |
| Journal | Journal of Dermatology |
| Volume | 38 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2011 Nov 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Dermatology
Cite this
}
Exclusive facial porokeratosis : Histopathologically showing follicular cornoid lamellae. / Lee, Yoonhee; Choi, Eung Ho.
In: Journal of Dermatology, Vol. 38, No. 11, 01.11.2011, p. 1072-1075.Research output: Contribution to journal › Article
TY - JOUR
T1 - Exclusive facial porokeratosis
T2 - Histopathologically showing follicular cornoid lamellae
AU - Lee, Yoonhee
AU - Choi, Eung Ho
PY - 2011/11/1
Y1 - 2011/11/1
N2 - Porokeratosis is a heterogeneous group of disorders that are mostly inherited in an autosomal dominant fashion. It has a wide variety of clinical manifestations with a characteristic histological finding of cornoid lamella. Porokeratosis usually affects the trunk or the extremities. Exclusive facial lesions are rare, although 15% of patients with disseminated, superficial, actinic porokeratosis do have facial lesions. Herein, we discuss the case of a 25-year-old woman who noticed the appearance of well-defined, brownish, macular lesions located on both cheeks. She had no other symptoms. A skin examination showed well-demarcated, multiple, brownish macules with raised hyperkeratotic borders on both cheeks and a half-palm-sized, arcuate-shaped lesion formed by grouped macules on the right cheek. No other parts of the body were affected. Histopathological examination of a biopsy specimen obtained from the hyperkeratotic margin gave a diagnosis of porokeratosis with follicular involvement of the cornoid lamellae. Topical pimecrolimus was applied twice a day to the lesions, although little improvement was achieved after 2 months.
AB - Porokeratosis is a heterogeneous group of disorders that are mostly inherited in an autosomal dominant fashion. It has a wide variety of clinical manifestations with a characteristic histological finding of cornoid lamella. Porokeratosis usually affects the trunk or the extremities. Exclusive facial lesions are rare, although 15% of patients with disseminated, superficial, actinic porokeratosis do have facial lesions. Herein, we discuss the case of a 25-year-old woman who noticed the appearance of well-defined, brownish, macular lesions located on both cheeks. She had no other symptoms. A skin examination showed well-demarcated, multiple, brownish macules with raised hyperkeratotic borders on both cheeks and a half-palm-sized, arcuate-shaped lesion formed by grouped macules on the right cheek. No other parts of the body were affected. Histopathological examination of a biopsy specimen obtained from the hyperkeratotic margin gave a diagnosis of porokeratosis with follicular involvement of the cornoid lamellae. Topical pimecrolimus was applied twice a day to the lesions, although little improvement was achieved after 2 months.
UR - http://www.scopus.com/inward/record.url?scp=80355144452&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80355144452&partnerID=8YFLogxK
U2 - 10.1111/j.1346-8138.2011.01260.x
DO - 10.1111/j.1346-8138.2011.01260.x
M3 - Article
C2 - 21933257
AN - SCOPUS:80355144452
VL - 38
SP - 1072
EP - 1075
JO - Journal of Dermatology
JF - Journal of Dermatology
SN - 0385-2407
IS - 11
ER -