Extramarginal excision is preferable for hypertrophic scars

Jung U. Shin, Jihun Park, JuHee Lee, Kwanghoon Lee, Yong Ook Kim, Chae Ok Yun, Won Jai Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Recently, higher proliferative activity and collagen production in the peripheral parts of keloids have been reported. Therefore, we hypothesized that insufficient removal of active proliferating and collagen-producing fibroblasts at the scar margin might cause a high recurrence rate of hypertrophic scars and keloids. To address this hypothesis, we evaluated the influence of surgical margins on the recurrence of hypertrophic scars and compared the recurrence rates between intramarginal excision and extramarginal excision. Methods: A retrospective review was performed of patients with car tire injury-induced hypertrophic scars treated by surgical excision from 2004 to 2010. To evaluate the influence of surgical margins on the recurrence of hypertrophic scars, we divided these patients into two groups, the intramarginal excision group and the extramarginal excision group, and compared the recurrence rate. Results: A total of 15 patients with car tire injury-induced hypertrophic scars were treated with surgical excision and skin grafting. The recurrence rate in those with intramarginal excision was significantly higher than in those with extramarginal excision. All patients treated with intramarginal excision experienced hypertrophic scar recurrence within six months. Three of nine patients exhibited recurrence when the hypertrophic scars were excised with a 3-5 mm margin. Conclusion: Extramarginal excision with complete removal of the abnormal collagen bundles followed by skin grafting is a viable alternative to reconstruction of the foot after hypertrophic scar excision, and this treatment can effectively decrease issues related to recurrence.

Original languageEnglish
Pages (from-to)1138-1144
Number of pages7
JournalInternational Journal of Dermatology
Volume53
Issue number9
DOIs
Publication statusPublished - 2014 Jan 1

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Hypertrophic Cicatrix
Recurrence
Keloid
Skin Transplantation
Collagen
Wounds and Injuries
Cicatrix
Foot
Fibroblasts

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Shin, Jung U. ; Park, Jihun ; Lee, JuHee ; Lee, Kwanghoon ; Kim, Yong Ook ; Yun, Chae Ok ; Lee, Won Jai. / Extramarginal excision is preferable for hypertrophic scars. In: International Journal of Dermatology. 2014 ; Vol. 53, No. 9. pp. 1138-1144.
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abstract = "Recently, higher proliferative activity and collagen production in the peripheral parts of keloids have been reported. Therefore, we hypothesized that insufficient removal of active proliferating and collagen-producing fibroblasts at the scar margin might cause a high recurrence rate of hypertrophic scars and keloids. To address this hypothesis, we evaluated the influence of surgical margins on the recurrence of hypertrophic scars and compared the recurrence rates between intramarginal excision and extramarginal excision. Methods: A retrospective review was performed of patients with car tire injury-induced hypertrophic scars treated by surgical excision from 2004 to 2010. To evaluate the influence of surgical margins on the recurrence of hypertrophic scars, we divided these patients into two groups, the intramarginal excision group and the extramarginal excision group, and compared the recurrence rate. Results: A total of 15 patients with car tire injury-induced hypertrophic scars were treated with surgical excision and skin grafting. The recurrence rate in those with intramarginal excision was significantly higher than in those with extramarginal excision. All patients treated with intramarginal excision experienced hypertrophic scar recurrence within six months. Three of nine patients exhibited recurrence when the hypertrophic scars were excised with a 3-5 mm margin. Conclusion: Extramarginal excision with complete removal of the abnormal collagen bundles followed by skin grafting is a viable alternative to reconstruction of the foot after hypertrophic scar excision, and this treatment can effectively decrease issues related to recurrence.",
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Extramarginal excision is preferable for hypertrophic scars. / Shin, Jung U.; Park, Jihun; Lee, JuHee; Lee, Kwanghoon; Kim, Yong Ook; Yun, Chae Ok; Lee, Won Jai.

In: International Journal of Dermatology, Vol. 53, No. 9, 01.01.2014, p. 1138-1144.

Research output: Contribution to journalArticle

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AU - Lee, JuHee

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AU - Kim, Yong Ook

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AU - Lee, Won Jai

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