Abstract
A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.
| Original language | English |
|---|---|
| Pages (from-to) | 3180-3182 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 41 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - 2002 Sep 2 |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
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Fabrication of carbohydrate chips for studying protein-carbohydrate interactions. / Park, Sungjin; Shin, Injae.
In: Angewandte Chemie - International Edition, Vol. 41, No. 17, 02.09.2002, p. 3180-3182.Research output: Contribution to journal › Article
TY - JOUR
T1 - Fabrication of carbohydrate chips for studying protein-carbohydrate interactions
AU - Park, Sungjin
AU - Shin, Injae
PY - 2002/9/2
Y1 - 2002/9/2
N2 - A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.
AB - A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.
UR - http://www.scopus.com/inward/record.url?scp=0037009016&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037009016&partnerID=8YFLogxK
U2 - 10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S
DO - 10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S
M3 - Article
C2 - 12207382
AN - SCOPUS:0037009016
VL - 41
SP - 3180
EP - 3182
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 17
ER -