Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

Sungjin Park, Injae Shin

Research output: Contribution to journalArticle

229 Citations (Scopus)

Abstract

A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.

Original languageEnglish
Pages (from-to)3180-3182
Number of pages3
JournalAngewandte Chemie - International Edition
Volume41
Issue number17
DOIs
Publication statusPublished - 2002 Sep 2

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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