Fabrication of chemical microarrays by efficient immobilization of hydrazide-linked substances on epoxide-coated glass surfaces

Myung Ryul Lee, Injae Shin

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

(Chemical Equation Presented) Fixed to the spot: A new, efficient, and simple immobilization technique for the construction of chemical microarrays has been developed. This technique is applicable to the site-selective attachment of diverse substances, including small molecules, carbohydrates, and peptides, to glass slides (see picture). The chemical microarrays fabricated by using this method were applied to screening peptide and small-molecule binding to proteins.

Original languageEnglish
Pages (from-to)2881-2884
Number of pages4
JournalAngewandte Chemie - International Edition
Volume44
Issue number19
DOIs
Publication statusPublished - 2005 May 6

Fingerprint

Epoxy Compounds
Microarrays
Peptides
Fabrication
Glass
Molecules
Carbohydrates
Screening
Proteins

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

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