Fabrication of poly(L-lactide)-block-poly(ethylene glycol)-block-poly(L- lactide) triblock copolymer thin films with nanochannels: An AFM study

Sung Wook Choi, Yongwoo Kim, In Woo Cheong, Jung Hyun Kim

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4 Citations (Scopus)

Abstract

This paper aims to report the fabrication of biodegradable thin films with micro-domains of cylindrical nanochannels through the solvent-induced microphase separation of poly(L-lactide)-block-poly(ethylene glycol)-block-poly(L-lactide) (PLA-b-PEG-fe-PLA) triblock copolymers with different block ratios. In our experimental scope, an increase in each of the block lengths of the PLA and PEG blocks led to both a variation in the average number density (146 to 32 per 100 μm2) and the size of the micro-domains (140 to 427 nm). Analyses by atomic force microscopy (AFM) and fluorescence microscopy indicated that the hydrophilic PEG nanochannels were dispersed in the PLA matrix of the PLA-b-PEG-b-PLA films. We demonstrated that the micro-domain morphology could be controlled not only by the block length of PEG, but also by the solvent evaporation conditions.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalMacromolecular Rapid Communications
Volume29
Issue number2
DOIs
Publication statusPublished - 2008 Jan 17

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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