Facial diplegia in Plasmodium vivax malaria

Jae Eun Sim, Young Chul Choi, Won Joo Kim

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background Facial diplegia has diverse etiologies, including viral and bacterial infections such as diphtheria, syphilis and Lyme disease, and also protozoal infection in very rarely cases. Case Report A 20-year-old male patient was admitted to our hospital due to bilateral weakness of the upper and lower facial muscles. Examination revealed that the patient had a facial diplegia of the peripheral type. A peripheral blood smear demonstrated the presence of the asexual trophozoite stage of Plasmodium vivax with ring-form trophozoites, which led to a diagnosis of malaria. A serum work-up revealed increased IgG titers of antibodies to myelin-associated glycoprotein and ganglioside GD1b. The patient was administered antimalarial treatment, 1 week after which he showed signs of recovery. To our knowledge, this is the first case of facial diplegia after malaria infection, providing evidence that the mechanism underlying the condition is related to immune-mediated disease. Conclusions Facial diplegia can manifest after P. vivax infection.

Original languageEnglish
Pages (from-to)102-103
Number of pages2
JournalJournal of Clinical Neurology (Korea)
Volume6
Issue number2
DOIs
Publication statusPublished - 2010 Jun

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Vivax Malaria
Malaria
Plasmodium vivax
Trophozoites
Myelin-Associated Glycoprotein
Facial Muscles
Diphtheria
Lyme Disease
Immune System Diseases
Antimalarials
Virus Diseases
Syphilis
Infection
Bacterial Infections
Immunoglobulin G
Antibodies
Serum
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Sim, Jae Eun ; Choi, Young Chul ; Kim, Won Joo. / Facial diplegia in Plasmodium vivax malaria. In: Journal of Clinical Neurology (Korea). 2010 ; Vol. 6, No. 2. pp. 102-103.
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Facial diplegia in Plasmodium vivax malaria. / Sim, Jae Eun; Choi, Young Chul; Kim, Won Joo.

In: Journal of Clinical Neurology (Korea), Vol. 6, No. 2, 06.2010, p. 102-103.

Research output: Contribution to journalArticle

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N2 - Background Facial diplegia has diverse etiologies, including viral and bacterial infections such as diphtheria, syphilis and Lyme disease, and also protozoal infection in very rarely cases. Case Report A 20-year-old male patient was admitted to our hospital due to bilateral weakness of the upper and lower facial muscles. Examination revealed that the patient had a facial diplegia of the peripheral type. A peripheral blood smear demonstrated the presence of the asexual trophozoite stage of Plasmodium vivax with ring-form trophozoites, which led to a diagnosis of malaria. A serum work-up revealed increased IgG titers of antibodies to myelin-associated glycoprotein and ganglioside GD1b. The patient was administered antimalarial treatment, 1 week after which he showed signs of recovery. To our knowledge, this is the first case of facial diplegia after malaria infection, providing evidence that the mechanism underlying the condition is related to immune-mediated disease. Conclusions Facial diplegia can manifest after P. vivax infection.

AB - Background Facial diplegia has diverse etiologies, including viral and bacterial infections such as diphtheria, syphilis and Lyme disease, and also protozoal infection in very rarely cases. Case Report A 20-year-old male patient was admitted to our hospital due to bilateral weakness of the upper and lower facial muscles. Examination revealed that the patient had a facial diplegia of the peripheral type. A peripheral blood smear demonstrated the presence of the asexual trophozoite stage of Plasmodium vivax with ring-form trophozoites, which led to a diagnosis of malaria. A serum work-up revealed increased IgG titers of antibodies to myelin-associated glycoprotein and ganglioside GD1b. The patient was administered antimalarial treatment, 1 week after which he showed signs of recovery. To our knowledge, this is the first case of facial diplegia after malaria infection, providing evidence that the mechanism underlying the condition is related to immune-mediated disease. Conclusions Facial diplegia can manifest after P. vivax infection.

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