Facile Access to 3,4-Disubstituted 2 H -Chromenes via Domino [4+2] Annulation

Sure Siva Prasad, Dirgha Raj Joshi, Ikyon Kim

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A highly efficient synthetic route to polysubstituted 2 H -chromenes was developed utilizing a domino O-alkylation/intramolecular Horner-Wadsworth-Emmons (HWE) olefination of diarylmethylphosphonates, which were readily accessed via Lewis acid mediated one-pot three-component coupling of aldehydes, phenols, and triethyl phosphite.

Original languageEnglish
Pages (from-to)1503-1512
Number of pages10
JournalSynthesis (Germany)
Volume53
Issue number8
DOIs
Publication statusPublished - 2021 Apr 20

Bibliographical note

Funding Information:
We thank the National Research Foundation of Korea (NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961) for generous financial support.National ReeachFoundatonofKoeaNRF2018R1A6A1A03023718National ReseachFoundaionofKoea(NRF2020R1A2C2005961)

Publisher Copyright:
© 2021 Georg Thieme Verlag. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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