Facile Access to 3,4-Disubstituted 2 H -Chromenes via Domino [4+2] Annulation

Sure Siva Prasad, Dirgha Raj Joshi, Ikyon Kim

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


A highly efficient synthetic route to polysubstituted 2 H -chromenes was developed utilizing a domino O-alkylation/intramolecular Horner-Wadsworth-Emmons (HWE) olefination of diarylmethylphosphonates, which were readily accessed via Lewis acid mediated one-pot three-component coupling of aldehydes, phenols, and triethyl phosphite.

Original languageEnglish
Article numberss-2020-f0516-op
JournalSynthesis (Germany)
Publication statusAccepted/In press - 2020

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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