Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

Joong Gon Kim; Doo Ok Jang

doi:10.1055/s-0030-1258518

Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

Joong Gon Kim, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.

Original language	English
Article number	U04610ST
Pages (from-to)	2093-2096
Number of pages	4
Journal	Synlett
Issue number	14
DOIs	https://doi.org/10.1055/s-0030-1258518
Publication status	Published - 2010

All Science Journal Classification (ASJC) codes

Organic Chemistry

Access to Document

10.1055/s-0030-1258518

Cite this

@article{6fa438fd0e4e4dafbde5375149580d4a,

title = "Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions",

abstract = "We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.",

author = "Kim, {Joong Gon} and Jang, {Doo Ok}",

year = "2010",

doi = "10.1055/s-0030-1258518",

language = "English",

pages = "2093--2096",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "14",

}

TY - JOUR

T1 - Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

AU - Kim, Joong Gon

AU - Jang, Doo Ok

PY - 2010

Y1 - 2010

N2 - We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.

AB - We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.

UR - http://www.scopus.com/inward/record.url?scp=77956014076&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77956014076&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1258518

DO - 10.1055/s-0030-1258518

M3 - Article

AN - SCOPUS:77956014076

SP - 2093

EP - 2096

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 14

M1 - U04610ST

ER -

Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this