Abstract
We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.
| Original language | English |
|---|---|
| Article number | U04610ST |
| Pages (from-to) | 2093-2096 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - 2010 Sep 1 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Cite this
Kim, J. G., & Jang, D. O. (2010). Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions. Synlett, (14), 2093-2096. [U04610ST]. https://doi.org/10.1055/s-0030-1258518