Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

Joong Gon Kim, Doo Ok Jang

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.

Original languageEnglish
Article numberU04610ST
Pages (from-to)2093-2096
Number of pages4
JournalSynlett
Issue number14
DOIs
Publication statusPublished - 2010 Sep 1

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Iodine
Amines
Esters
Amino Acids
Catalysts

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions. / Kim, Joong Gon; Jang, Doo Ok.

In: Synlett, No. 14, U04610ST, 01.09.2010, p. 2093-2096.

Research output: Contribution to journalArticle

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