Facile and highly efficient N-formylation of amines using a catalytic amount of iodine under solvent-free conditions

Joong Gon Kim, Doo Ok Jang

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

We developed a simple, practical, and catalytic method for the N-formylation of a wide variety of amines in the presence of molecular iodine as a catalyst under solvent-free conditions. This reaction is applicable to the chemoselective N-formylation of amino groups and -amino acid esters without epimerization.

Original languageEnglish
Article numberU04610ST
Pages (from-to)2093-2096
Number of pages4
JournalSynlett
Issue number14
DOIs
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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