Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process

Youngeun Jung; Ikyon Kim

doi:10.1016/j.tet.2012.07.068

Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process

Youngeun Jung, Ikyon Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Successful implementation of a sequential Pd-catalyzed Sonogashira cross-coupling/iodine-promoted 5-exo-dig cyclization procedure with pyridines bearing a terminal alkyne moiety provided direct and straightforward access to a diverse array of 3-acylated indolizines under mild conditions.

Original language	English
Pages (from-to)	8198-8206
Number of pages	9
Journal	Tetrahedron
Volume	68
Issue number	39
DOIs	https://doi.org/10.1016/j.tet.2012.07.068
Publication status	Published - 2012 Sept 30

Bibliographical note

Funding Information:
We thank Yonsei University for financial support.

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2012.07.068

Cite this

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title = "Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process",

abstract = "Successful implementation of a sequential Pd-catalyzed Sonogashira cross-coupling/iodine-promoted 5-exo-dig cyclization procedure with pyridines bearing a terminal alkyne moiety provided direct and straightforward access to a diverse array of 3-acylated indolizines under mild conditions.",

author = "Youngeun Jung and Ikyon Kim",

note = "Funding Information: We thank Yonsei University for financial support. ",

year = "2012",

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doi = "10.1016/j.tet.2012.07.068",

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AU - Jung, Youngeun

AU - Kim, Ikyon

N1 - Funding Information: We thank Yonsei University for financial support.

PY - 2012/9/30

Y1 - 2012/9/30

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AB - Successful implementation of a sequential Pd-catalyzed Sonogashira cross-coupling/iodine-promoted 5-exo-dig cyclization procedure with pyridines bearing a terminal alkyne moiety provided direct and straightforward access to a diverse array of 3-acylated indolizines under mild conditions.

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DO - 10.1016/j.tet.2012.07.068

M3 - Article

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VL - 68

SP - 8198

EP - 8206

JO - Tetrahedron

JF - Tetrahedron

IS - 39

ER -

Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

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