Facile preparation of carbohydrate microarrays by site-specific, covalent immobilization of unmodified carbohydrates on hydrazide-coated glass slides

Myung Ryul Lee, Injae Shin

Research output: Contribution to journalArticle

145 Citations (Scopus)

Abstract

(Chemical Equation Presented) A new, simple and efficient immobilization method to attach mono-, di-, oligo-, and polysaccharides to hydrazide-coated glass slides was developed. Protein and cell-binding experiments show that the carbohydrate microarrays prepared by this method are applicable for the rapid analysis of protein-carbohydrate interactions and fast detection of pathogens.

Original languageEnglish
Pages (from-to)4269-4272
Number of pages4
JournalOrganic Letters
Volume7
Issue number19
DOIs
Publication statusPublished - 2005 Sep 15

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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