A facile two-step synthesis of a series of benzo-fused 2,8-dioxabicyclo[3.3.1]nonane derivatives is described, featuring a domino Knoevenagel condensation/intramolecular hetero-Diels-Alder reaction sequence.
Bibliographical noteFunding Information:
We thank the Center for Biological Modulators and Korea Research Institute of Chemical Technology for generous financial support.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry