Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer

Jong Chan Youn, Young Hoon Youn, Tae Il Kim, Seung Woo Park, Se Joon Lee, Si Young Song, Jae Bock Chung, Yongchan Lee

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background/Aims: Endoscopic mucosal resection (EMR) has been widely accepted as a treatment option for early gastric cancer (EGC) in selected cases. The purposes of this study were to evaluate the long-term outcomes and the factors affecting the clinical outcomes, of EMR performed in EGC. Methodology: Between April 1996 and March 2005, 147 patients have undergone EMR to treat EGC at Yonsei University Medical Center, Seoul, Korea. We assessed the clinical outcomes of the EMR for EGC in a long-term follow-up period. We also reviewed the medical records of the patients including demographic data, endoscopic characteristics of the lesion and histopathologic findings. Results: The histopathologic evaluations after the EMR treatment showed that overall complete resection rate was 84.6% (126/149) while complete resection rate of 93.5% was achieved in mucosal cancers (115/123). The success of complete resection was significantly affected by endoscopic gross type (depressed lesion), the degree of differentiation, and the depth of invasion, independently. There were only 5 cases of local recurrence during the follow-up periods, and the recurred or incompletely resected lesions were successfully treated by salvage operation or endoscopic retreatment. There was no disease-related or treatment-related mortality during the follow-up period. Conclusions: EMR is a good and safe curative treatment option with feasible clinical outcomes in patients with EGC. It must be emphasized that a proper selection of candidates is mandatory to improve the clinical outcome of EMR in EGC.

Original languageEnglish
Pages (from-to)643-647
Number of pages5
JournalHepato-Gastroenterology
Volume53
Issue number70
Publication statusPublished - 2006 Jul 1

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Stomach Neoplasms
Retreatment
Therapeutics
Korea
Endoscopic Mucosal Resection
Medical Records
Demography
Recurrence
Mortality
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Hepatology
  • Gastroenterology

Cite this

Youn, J. C., Youn, Y. H., Kim, T. I., Park, S. W., Lee, S. J., Song, S. Y., ... Lee, Y. (2006). Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer. Hepato-Gastroenterology, 53(70), 643-647.
Youn, Jong Chan ; Youn, Young Hoon ; Kim, Tae Il ; Park, Seung Woo ; Lee, Se Joon ; Song, Si Young ; Chung, Jae Bock ; Lee, Yongchan. / Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer. In: Hepato-Gastroenterology. 2006 ; Vol. 53, No. 70. pp. 643-647.
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Youn, JC, Youn, YH, Kim, TI, Park, SW, Lee, SJ, Song, SY, Chung, JB & Lee, Y 2006, 'Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer', Hepato-Gastroenterology, vol. 53, no. 70, pp. 643-647.

Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer. / Youn, Jong Chan; Youn, Young Hoon; Kim, Tae Il; Park, Seung Woo; Lee, Se Joon; Song, Si Young; Chung, Jae Bock; Lee, Yongchan.

In: Hepato-Gastroenterology, Vol. 53, No. 70, 01.07.2006, p. 643-647.

Research output: Contribution to journalArticle

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AU - Youn, Jong Chan

AU - Youn, Young Hoon

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AU - Lee, Yongchan

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Youn JC, Youn YH, Kim TI, Park SW, Lee SJ, Song SY et al. Factors affecting long-term clinical outcomes of endoscopic mucosal resection of early gastric cancer. Hepato-Gastroenterology. 2006 Jul 1;53(70):643-647.