Factors affecting the trajectory of health-related quality of life in COPD patients

J. Y. Yoo, Y. S. Kim, S. S. Kim, Hyangkyu Lee, C. G. Park, Euigeum Oh, Y. M. Oh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Health-related quality of life (HRQoL) is an important issue in patients with chronic obstructive pulmonary disease (COPD), as in other chronic illness groups. However, there is limited information on longitudinal changes in HR-QoL over time with the illness trajectory model. OBJECTIVE : To identify different patterns of HR-QoL changes in longitudinal data, and reveal potential predictors affecting these trajectories. METHODS : Subjects with COPD (n=249) were drawn from the Korean Obstructive Lung Disease cohort, which was conducted from 2005 to 2012. Longitudinal data were drawn from the St George's Respiratory Questionnaire and clinical measures. Growth mixture modelling was used to estimate distinct patterns, and binary and ordinal logistic regression were used to determine factors affecting different trajectory HR-QoL patterns using STATA 12.0. RESULT S : Five distinct HR-QoL patterns were identified. Results show that the level of baseline HR-QoL was significantly associated with age, the BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity) index at baseline, sleep disturbance, experience of exacerbation in previous year and level of depression. Distinct patterns in HR-QoL that improved vs. worsened were significantly associated with BODE index, number of respiratory symptoms and depression level. CONCLUS IONS : These findings suggest that comprehensive assessment and individualised management programmes are needed to improve HR-QoL in COPD patients.

Original languageEnglish
Pages (from-to)738-746
Number of pages9
JournalInternational Journal of Tuberculosis and Lung Disease
Volume20
Issue number6
DOIs
Publication statusPublished - 2016 Jun 1

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Chronic Obstructive Pulmonary Disease
Quality of Life
Obstructive Lung Diseases
Respiratory Insufficiency
Dyspnea
Sleep
Body Mass Index
Chronic Disease
Logistic Models
Exercise
Depression
Growth
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

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title = "Factors affecting the trajectory of health-related quality of life in COPD patients",
abstract = "Health-related quality of life (HRQoL) is an important issue in patients with chronic obstructive pulmonary disease (COPD), as in other chronic illness groups. However, there is limited information on longitudinal changes in HR-QoL over time with the illness trajectory model. OBJECTIVE : To identify different patterns of HR-QoL changes in longitudinal data, and reveal potential predictors affecting these trajectories. METHODS : Subjects with COPD (n=249) were drawn from the Korean Obstructive Lung Disease cohort, which was conducted from 2005 to 2012. Longitudinal data were drawn from the St George's Respiratory Questionnaire and clinical measures. Growth mixture modelling was used to estimate distinct patterns, and binary and ordinal logistic regression were used to determine factors affecting different trajectory HR-QoL patterns using STATA 12.0. RESULT S : Five distinct HR-QoL patterns were identified. Results show that the level of baseline HR-QoL was significantly associated with age, the BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity) index at baseline, sleep disturbance, experience of exacerbation in previous year and level of depression. Distinct patterns in HR-QoL that improved vs. worsened were significantly associated with BODE index, number of respiratory symptoms and depression level. CONCLUS IONS : These findings suggest that comprehensive assessment and individualised management programmes are needed to improve HR-QoL in COPD patients.",
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Factors affecting the trajectory of health-related quality of life in COPD patients. / Yoo, J. Y.; Kim, Y. S.; Kim, S. S.; Lee, Hyangkyu; Park, C. G.; Oh, Euigeum; Oh, Y. M.

In: International Journal of Tuberculosis and Lung Disease, Vol. 20, No. 6, 01.06.2016, p. 738-746.

Research output: Contribution to journalArticle

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AU - Yoo, J. Y.

AU - Kim, Y. S.

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AU - Oh, Euigeum

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N2 - Health-related quality of life (HRQoL) is an important issue in patients with chronic obstructive pulmonary disease (COPD), as in other chronic illness groups. However, there is limited information on longitudinal changes in HR-QoL over time with the illness trajectory model. OBJECTIVE : To identify different patterns of HR-QoL changes in longitudinal data, and reveal potential predictors affecting these trajectories. METHODS : Subjects with COPD (n=249) were drawn from the Korean Obstructive Lung Disease cohort, which was conducted from 2005 to 2012. Longitudinal data were drawn from the St George's Respiratory Questionnaire and clinical measures. Growth mixture modelling was used to estimate distinct patterns, and binary and ordinal logistic regression were used to determine factors affecting different trajectory HR-QoL patterns using STATA 12.0. RESULT S : Five distinct HR-QoL patterns were identified. Results show that the level of baseline HR-QoL was significantly associated with age, the BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity) index at baseline, sleep disturbance, experience of exacerbation in previous year and level of depression. Distinct patterns in HR-QoL that improved vs. worsened were significantly associated with BODE index, number of respiratory symptoms and depression level. CONCLUS IONS : These findings suggest that comprehensive assessment and individualised management programmes are needed to improve HR-QoL in COPD patients.

AB - Health-related quality of life (HRQoL) is an important issue in patients with chronic obstructive pulmonary disease (COPD), as in other chronic illness groups. However, there is limited information on longitudinal changes in HR-QoL over time with the illness trajectory model. OBJECTIVE : To identify different patterns of HR-QoL changes in longitudinal data, and reveal potential predictors affecting these trajectories. METHODS : Subjects with COPD (n=249) were drawn from the Korean Obstructive Lung Disease cohort, which was conducted from 2005 to 2012. Longitudinal data were drawn from the St George's Respiratory Questionnaire and clinical measures. Growth mixture modelling was used to estimate distinct patterns, and binary and ordinal logistic regression were used to determine factors affecting different trajectory HR-QoL patterns using STATA 12.0. RESULT S : Five distinct HR-QoL patterns were identified. Results show that the level of baseline HR-QoL was significantly associated with age, the BODE (Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity) index at baseline, sleep disturbance, experience of exacerbation in previous year and level of depression. Distinct patterns in HR-QoL that improved vs. worsened were significantly associated with BODE index, number of respiratory symptoms and depression level. CONCLUS IONS : These findings suggest that comprehensive assessment and individualised management programmes are needed to improve HR-QoL in COPD patients.

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