Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients

Hyun Wook Kim, Hyun Chang Jae, Young Park Sun, Jin Moon Sung, Ki Kim Dong, Eun Lee Jung, SeungHyeok Han, Seok Kim Beum, Shin-Wook Kang, Hun Choi Kyu, Young Lee Ho, Dae Suk Han

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with hypokalemia were associated with older age and the presence of diabetes mellitus. Serum albumin, calcium-phosphate product, triglyceride, body mass index, protein nitrogen appearance, and lean body mass assessed by creatinine kinetics were significantly lower as compared to those without hypokalemia. Serum C-reactive protein was significantly higher in the patients with hypokalemia. Multivariate stepwise linear regression analysis revealed that the serum albumin level and the ultrafiltration volume at the peritoneal equilibration test were independent factors associated with hypokalemia. This suggests that the serum potassium level may be an important nutritional marker in CAPD patients. Further longitudinal investigation is needed to clarify this relationship.

Original languageEnglish
Pages (from-to)102-110
Number of pages9
JournalElectrolyte and Blood Pressure
Volume5
Issue number2
DOIs
Publication statusPublished - 2007 Jan 1

Fingerprint

Hypokalemia
Continuous Ambulatory Peritoneal Dialysis
Serum Albumin
Ultrafiltration
C-Reactive Protein
Blood Proteins
Linear Models
Creatinine
Diabetes Mellitus
Potassium
Triglycerides
Body Mass Index
Nitrogen
Regression Analysis
Maintenance
Serum
Proteins

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Kim, H. W., Jae, H. C., Sun, Y. P., Sung, J. M., Dong, K. K., Jung, E. L., ... Han, D. S. (2007). Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients. Electrolyte and Blood Pressure, 5(2), 102-110. https://doi.org/10.5049/EBP.2007.5.2.102
Kim, Hyun Wook ; Jae, Hyun Chang ; Sun, Young Park ; Sung, Jin Moon ; Dong, Ki Kim ; Jung, Eun Lee ; Han, SeungHyeok ; Beum, Seok Kim ; Kang, Shin-Wook ; Kyu, Hun Choi ; Ho, Young Lee ; Han, Dae Suk. / Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients. In: Electrolyte and Blood Pressure. 2007 ; Vol. 5, No. 2. pp. 102-110.
@article{fd99b88e8a7d4e2d9e3d3163deccf3ba,
title = "Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients",
abstract = "Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with hypokalemia were associated with older age and the presence of diabetes mellitus. Serum albumin, calcium-phosphate product, triglyceride, body mass index, protein nitrogen appearance, and lean body mass assessed by creatinine kinetics were significantly lower as compared to those without hypokalemia. Serum C-reactive protein was significantly higher in the patients with hypokalemia. Multivariate stepwise linear regression analysis revealed that the serum albumin level and the ultrafiltration volume at the peritoneal equilibration test were independent factors associated with hypokalemia. This suggests that the serum potassium level may be an important nutritional marker in CAPD patients. Further longitudinal investigation is needed to clarify this relationship.",
author = "Kim, {Hyun Wook} and Jae, {Hyun Chang} and Sun, {Young Park} and Sung, {Jin Moon} and Dong, {Ki Kim} and Jung, {Eun Lee} and SeungHyeok Han and Beum, {Seok Kim} and Shin-Wook Kang and Kyu, {Hun Choi} and Ho, {Young Lee} and Han, {Dae Suk}",
year = "2007",
month = "1",
day = "1",
doi = "10.5049/EBP.2007.5.2.102",
language = "English",
volume = "5",
pages = "102--110",
journal = "Electrolyte and Blood Pressure",
issn = "1738-5997",
publisher = "Korean Society of Electrolyte and Blood Pressure Research",
number = "2",

}

Kim, HW, Jae, HC, Sun, YP, Sung, JM, Dong, KK, Jung, EL, Han, S, Beum, SK, Kang, S-W, Kyu, HC, Ho, YL & Han, DS 2007, 'Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients', Electrolyte and Blood Pressure, vol. 5, no. 2, pp. 102-110. https://doi.org/10.5049/EBP.2007.5.2.102

Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients. / Kim, Hyun Wook; Jae, Hyun Chang; Sun, Young Park; Sung, Jin Moon; Dong, Ki Kim; Jung, Eun Lee; Han, SeungHyeok; Beum, Seok Kim; Kang, Shin-Wook; Kyu, Hun Choi; Ho, Young Lee; Han, Dae Suk.

In: Electrolyte and Blood Pressure, Vol. 5, No. 2, 01.01.2007, p. 102-110.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Factors associated with hypokalemia in continuous ambulatory peritoneal dialysis patients

AU - Kim, Hyun Wook

AU - Jae, Hyun Chang

AU - Sun, Young Park

AU - Sung, Jin Moon

AU - Dong, Ki Kim

AU - Jung, Eun Lee

AU - Han, SeungHyeok

AU - Beum, Seok Kim

AU - Kang, Shin-Wook

AU - Kyu, Hun Choi

AU - Ho, Young Lee

AU - Han, Dae Suk

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with hypokalemia were associated with older age and the presence of diabetes mellitus. Serum albumin, calcium-phosphate product, triglyceride, body mass index, protein nitrogen appearance, and lean body mass assessed by creatinine kinetics were significantly lower as compared to those without hypokalemia. Serum C-reactive protein was significantly higher in the patients with hypokalemia. Multivariate stepwise linear regression analysis revealed that the serum albumin level and the ultrafiltration volume at the peritoneal equilibration test were independent factors associated with hypokalemia. This suggests that the serum potassium level may be an important nutritional marker in CAPD patients. Further longitudinal investigation is needed to clarify this relationship.

AB - Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on maintenance CAPD treatment for at least six months. In univariate analysis, patients with hypokalemia were associated with older age and the presence of diabetes mellitus. Serum albumin, calcium-phosphate product, triglyceride, body mass index, protein nitrogen appearance, and lean body mass assessed by creatinine kinetics were significantly lower as compared to those without hypokalemia. Serum C-reactive protein was significantly higher in the patients with hypokalemia. Multivariate stepwise linear regression analysis revealed that the serum albumin level and the ultrafiltration volume at the peritoneal equilibration test were independent factors associated with hypokalemia. This suggests that the serum potassium level may be an important nutritional marker in CAPD patients. Further longitudinal investigation is needed to clarify this relationship.

UR - http://www.scopus.com/inward/record.url?scp=38649092366&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38649092366&partnerID=8YFLogxK

U2 - 10.5049/EBP.2007.5.2.102

DO - 10.5049/EBP.2007.5.2.102

M3 - Article

AN - SCOPUS:38649092366

VL - 5

SP - 102

EP - 110

JO - Electrolyte and Blood Pressure

JF - Electrolyte and Blood Pressure

SN - 1738-5997

IS - 2

ER -