Factors related to complete occlusion of arteriovenous malformations after gamma knife radiosurgery

Hee Chang Jong Hee Chang, Woo Chang Jin Woo Chang, Gou Park Yong Gou Park, Sup Chung Sang Sup Chung

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80 Citations (Scopus)

Abstract

Object. The authors sought to evaluate the effects of gamma knife radiosurgery (GKS) on cerebral arteriovenous malformations (AVMs) and the factors associated with complete occlusion. Methods. A total of 301 radiosurgical procedures for 277 cerebral AVMs were performed between December 1988 and December 1999. Two hundred seventy-eight lesions in 254 patients who were treated with GKS from May 1992 to December 1999 were analyzed. Several clinical and radiological parameters were evaluated. Conclusions. The total obliteration rate for the cases with an adequate radiological follow up of more than 2 years was 78.9%. In multivariate analysis, maximum diameter, angiographically delineated shape of the AVM nidus, and the number of draining veins significantly influenced the result of radiosurgery. In addition, margin radiation dose, Spetzler-Martin grade, and the flow pattern of the AVM nidus also had some influence on the outcome. In addition to the size, topography, and radiosurgical parameters of AVMs, it would seem to be necessary to consider the angioarchitectural and hemodynamic aspects to select proper candidates for radiosurgery.

Original languageEnglish
Pages (from-to)96-101
Number of pages6
JournalJournal of neurosurgery
Volume93
Issue numberSUPPL. 3
Publication statusPublished - 2000 Dec 1

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All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Jong Hee Chang, H. C., Jin Woo Chang, W. C., Yong Gou Park, G. P., & Sang Sup Chung, S. C. (2000). Factors related to complete occlusion of arteriovenous malformations after gamma knife radiosurgery. Journal of neurosurgery, 93(SUPPL. 3), 96-101.