False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence

Sinyoung Kim; Jong Han Lee; Jun Yong Choi; June Myung Kim; Hyon Suk Kim

doi:10.1128/CVI.00258-10

False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence

Sinyoung Kim, Jong Han Lee, Jun Yong Choi, June Myung Kim, Hyon Suk Kim

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

We retrospectively analyzed the performance of the Architect HIV antigen/antibody (Ag/Ab) combination assay in a tertiary health care center with a situation of low HIV prevalence. The specificity and positive predictive value (PPV) were 99.78% and 31.21%, respectively. However, the specificity and PPV could increase to 99.99% and 89.70% using an arbitrary cutoff value.

Original language	English
Pages (from-to)	1642-1644
Number of pages	3
Journal	Clinical and Vaccine Immunology
Volume	17
Issue number	10
DOIs	https://doi.org/10.1128/CVI.00258-10
Publication status	Published - 2010 Oct

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Clinical Biochemistry
Microbiology (medical)

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10.1128/CVI.00258-10

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AU - Kim, Hyon Suk

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False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence

Abstract

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