False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence

Sinyoung Kim, Jong Han Lee, Jun Yong Choi, June Myung Kim, Hyon Suk Kim

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We retrospectively analyzed the performance of the Architect HIV antigen/antibody (Ag/Ab) combination assay in a tertiary health care center with a situation of low HIV prevalence. The specificity and positive predictive value (PPV) were 99.78% and 31.21%, respectively. However, the specificity and PPV could increase to 99.99% and 89.70% using an arbitrary cutoff value.

Original languageEnglish
Pages (from-to)1642-1644
Number of pages3
JournalClinical and Vaccine Immunology
Volume17
Issue number10
DOIs
Publication statusPublished - 2010 Oct 1

Fingerprint

HIV Antigens
HIV Antibodies
Health care
Tertiary Care Centers
Assays
HIV
Delivery of Health Care
Antibodies

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

Cite this

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False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence. / Kim, Sinyoung; Lee, Jong Han; Choi, Jun Yong; Kim, June Myung; Kim, Hyon Suk.

In: Clinical and Vaccine Immunology, Vol. 17, No. 10, 01.10.2010, p. 1642-1644.

Research output: Contribution to journalArticle

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