Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection

Yong Duk Jeon; Namki Hong; Jung Ho Kim; Se Hee Park; Sung Bae Kim; In Ji Song; Hea Won Ann; Jin Young Ahn; Sun Bean Kim; Nam Su Ku; Kyungwon Lee; Dongeun Yong; June Myung Kim; Jun Yong Choi

doi:10.3947/ic.2016.48.1.31

Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection

Yong Duk Jeon, Namki Hong, Jung Ho Kim, Se Hee Park, Sung Bae Kim, In Ji Song, Hea Won Ann, Jin Young Ahn, Sun Bean Kim, Nam Su Ku, Kyungwon Lee, Dongeun Yong, June Myung Kim, Jun Yong Choi

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.

Original language	English
Pages (from-to)	31-35
Number of pages	5
Journal	Infection and Chemotherapy
Volume	48
Issue number	1
DOIs	https://doi.org/10.3947/ic.2016.48.1.31
Publication status	Published - 2016 Mar 1

Bibliographical note

Publisher Copyright:
©2016 by The Korean Society of Infectious Diseases.

All Science Journal Classification (ASJC) codes

Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3947/ic.2016.48.1.31

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Jeon, Y. D., Hong, N., Kim, J. H., Park, S. H., Kim, S. B., Song, I. J., Ann, H. W., Ahn, J. Y., Kim, S. B., Ku, N. S., Lee, K., Yong, D., Kim, J. M., & Choi, J. Y. (2016). Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection. Infection and Chemotherapy, 48(1), 31-35. https://doi.org/10.3947/ic.2016.48.1.31

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abstract = "The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.",

author = "Jeon, {Yong Duk} and Namki Hong and Kim, {Jung Ho} and Park, {Se Hee} and Kim, {Sung Bae} and Song, {In Ji} and Ann, {Hea Won} and Ahn, {Jin Young} and Kim, {Sun Bean} and Ku, {Nam Su} and Kyungwon Lee and Dongeun Yong and Kim, {June Myung} and Choi, {Jun Yong}",

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doi = "10.3947/ic.2016.48.1.31",

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AU - Jeon, Yong Duk

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AU - Kim, Sung Bae

AU - Song, In Ji

AU - Ann, Hea Won

AU - Ahn, Jin Young

AU - Kim, Sun Bean

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AB - The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.

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Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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