Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection

Yong Duk Jeon, Namki Hong, Jung Ho Kim, Se Hee Park, Sung Bae Kim, In Ji Song, Hea Won Ann, Jin Young Ahn, Sun Bean Kim, Nam Su Ku, Kyungwon Lee, Dongeun Yong, June Myung Kim, Jun Yong Choi

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Abstract

The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalInfection and Chemotherapy
Volume48
Issue number1
DOIs
Publication statusPublished - 2016 Mar 1

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All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)

Cite this

Jeon, Y. D., Hong, N., Kim, J. H., Park, S. H., Kim, S. B., Song, I. J., Ann, H. W., Ahn, J. Y., Kim, S. B., Ku, N. S., Lee, K., Yong, D., Kim, J. M., & Choi, J. Y. (2016). Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection. Infection and Chemotherapy, 48(1), 31-35. https://doi.org/10.3947/ic.2016.48.1.31