Abstract
The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
| Original language | English |
|---|---|
| Pages (from-to) | 31-35 |
| Number of pages | 5 |
| Journal | Infection and Chemotherapy |
| Volume | 48 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2016 Mar 1 |
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All Science Journal Classification (ASJC) codes
- Infectious Diseases
- Pharmacology (medical)
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Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection. / Jeon, Yong Duk; Hong, Namki; Kim, Jung Ho; Park, Se Hee; Kim, Sung Bae; Song, In Ji; Ann, Hea Won; Ahn, Jin Young; Kim, Sun Bean; Ku, Nam Su; Lee, Kyungwon; Yong, DongEun; Kim, June Myung; Choi, JunYong.
In: Infection and Chemotherapy, Vol. 48, No. 1, 01.03.2016, p. 31-35.Research output: Contribution to journal › Article
TY - JOUR
T1 - Fecal transplantation using a nasoenteric tube during an initial episode of severe clostridium difficile infection
AU - Jeon, Yong Duk
AU - Hong, Namki
AU - Kim, Jung Ho
AU - Park, Se Hee
AU - Kim, Sung Bae
AU - Song, In Ji
AU - Ann, Hea Won
AU - Ahn, Jin Young
AU - Kim, Sun Bean
AU - Ku, Nam Su
AU - Lee, Kyungwon
AU - Yong, DongEun
AU - Kim, June Myung
AU - Choi, JunYong
PY - 2016/3/1
Y1 - 2016/3/1
N2 - The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
AB - The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
UR - http://www.scopus.com/inward/record.url?scp=84969542931&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84969542931&partnerID=8YFLogxK
U2 - 10.3947/ic.2016.48.1.31
DO - 10.3947/ic.2016.48.1.31
M3 - Article
AN - SCOPUS:84969542931
VL - 48
SP - 31
EP - 35
JO - Infection and Chemotherapy
JF - Infection and Chemotherapy
SN - 2093-2340
IS - 1
ER -