Ferric(III) Chloride Catalyzed Halogenation Reaction of Alcohols and Carboxylic Acids Using α,α-Dichlorodiphenylmethane

Chang Hee Lee, Soo Min Lee, Byul Hana Min, Dong Su Kim, Chul-Ho Jun

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A new method for chlorination of alcohols and carboxylic acids, using α,α-dichlorodiphenylmethane as the chlorinating agent and FeCl 3 as the catalyst, was developed. The method enables conversions of various alcohols and carboxylic acids to their corresponding alkyl and acyl chlorides in high yields under mild conditions. Particulary interesting is the observation that the respective alkyl bromides and iodides can be generated from alcohols when either LiBr or LiI are present in the reaction mixtures.

Original languageEnglish
Pages (from-to)2468-2471
Number of pages4
JournalOrganic Letters
Volume20
Issue number8
DOIs
Publication statusPublished - 2018 Apr 20

Fingerprint

Halogenation
halogenation
Carboxylic Acids
carboxylic acids
Chlorides
alcohols
chlorides
Alcohols
acids
chlorination
Chlorination
Iodides
Bromides
iodides
bromides
catalysts
Catalysts
ferric chloride

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Lee, Chang Hee ; Lee, Soo Min ; Min, Byul Hana ; Kim, Dong Su ; Jun, Chul-Ho. / Ferric(III) Chloride Catalyzed Halogenation Reaction of Alcohols and Carboxylic Acids Using α,α-Dichlorodiphenylmethane. In: Organic Letters. 2018 ; Vol. 20, No. 8. pp. 2468-2471.
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Ferric(III) Chloride Catalyzed Halogenation Reaction of Alcohols and Carboxylic Acids Using α,α-Dichlorodiphenylmethane. / Lee, Chang Hee; Lee, Soo Min; Min, Byul Hana; Kim, Dong Su; Jun, Chul-Ho.

In: Organic Letters, Vol. 20, No. 8, 20.04.2018, p. 2468-2471.

Research output: Contribution to journalArticle

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