Fine Needle Aspiration Cytology of Small Cell Variant of Anaplastic Large Cell Lymphoma

A Case Report

Sung Eun Kim, SeHoon Kim, Beom Jin Lim, Soon Won Hong, Woo Ick Yang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

BACKGROUND: Small cell variant of anaplastic large cell lymphoma (ALCL) is a rare and still underrecognized variant of ALCL. In contrast to the classic type of ALCL, which is sometimes mistaken for carcinoma or sarcoma, the small cell variant may be misdiagnosed as a reactive lesion without a high index of suspicion. CASE: We present a case of small cell variant of ALCL occurring in a 14-year-old female. It posed great difficulty in the fine needle aspiration (FNA) diagnosis due to the rarity of large, atypical cells. A subsequent lymph node biopsy demonstrated the typical histologic and immunophenotypic findings of the small cell variant of ALCL. CONCLUSION: This case indicates that small cell variant of ALCL should always be considered in the FNA diagnosis of unusual-looking, heterogeneous lymphoid proliferations dominated by atypical small or medium-sized lymphoid cells, particularly in young patients.

Original languageEnglish
Pages (from-to)254-258
Number of pages5
JournalActa Cytologica
Volume48
Issue number2
DOIs
Publication statusPublished - 2004 Jan 1

Fingerprint

Fine Needle Biopsy
Cell Biology
Anaplastic Large-Cell Lymphoma
Small Cell Sarcoma
Diagnostic Errors
Lymph Nodes
Lymphocytes
Carcinoma
Biopsy
Anaplastic small cell lymphoma

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

Kim, Sung Eun ; Kim, SeHoon ; Lim, Beom Jin ; Hong, Soon Won ; Yang, Woo Ick. / Fine Needle Aspiration Cytology of Small Cell Variant of Anaplastic Large Cell Lymphoma : A Case Report. In: Acta Cytologica. 2004 ; Vol. 48, No. 2. pp. 254-258.
@article{db7df0ca23dd45f7a6b30ee76809c426,
title = "Fine Needle Aspiration Cytology of Small Cell Variant of Anaplastic Large Cell Lymphoma: A Case Report",
abstract = "BACKGROUND: Small cell variant of anaplastic large cell lymphoma (ALCL) is a rare and still underrecognized variant of ALCL. In contrast to the classic type of ALCL, which is sometimes mistaken for carcinoma or sarcoma, the small cell variant may be misdiagnosed as a reactive lesion without a high index of suspicion. CASE: We present a case of small cell variant of ALCL occurring in a 14-year-old female. It posed great difficulty in the fine needle aspiration (FNA) diagnosis due to the rarity of large, atypical cells. A subsequent lymph node biopsy demonstrated the typical histologic and immunophenotypic findings of the small cell variant of ALCL. CONCLUSION: This case indicates that small cell variant of ALCL should always be considered in the FNA diagnosis of unusual-looking, heterogeneous lymphoid proliferations dominated by atypical small or medium-sized lymphoid cells, particularly in young patients.",
author = "Kim, {Sung Eun} and SeHoon Kim and Lim, {Beom Jin} and Hong, {Soon Won} and Yang, {Woo Ick}",
year = "2004",
month = "1",
day = "1",
doi = "10.1159/000326327",
language = "English",
volume = "48",
pages = "254--258",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "2",

}

Fine Needle Aspiration Cytology of Small Cell Variant of Anaplastic Large Cell Lymphoma : A Case Report. / Kim, Sung Eun; Kim, SeHoon; Lim, Beom Jin; Hong, Soon Won; Yang, Woo Ick.

In: Acta Cytologica, Vol. 48, No. 2, 01.01.2004, p. 254-258.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fine Needle Aspiration Cytology of Small Cell Variant of Anaplastic Large Cell Lymphoma

T2 - A Case Report

AU - Kim, Sung Eun

AU - Kim, SeHoon

AU - Lim, Beom Jin

AU - Hong, Soon Won

AU - Yang, Woo Ick

PY - 2004/1/1

Y1 - 2004/1/1

N2 - BACKGROUND: Small cell variant of anaplastic large cell lymphoma (ALCL) is a rare and still underrecognized variant of ALCL. In contrast to the classic type of ALCL, which is sometimes mistaken for carcinoma or sarcoma, the small cell variant may be misdiagnosed as a reactive lesion without a high index of suspicion. CASE: We present a case of small cell variant of ALCL occurring in a 14-year-old female. It posed great difficulty in the fine needle aspiration (FNA) diagnosis due to the rarity of large, atypical cells. A subsequent lymph node biopsy demonstrated the typical histologic and immunophenotypic findings of the small cell variant of ALCL. CONCLUSION: This case indicates that small cell variant of ALCL should always be considered in the FNA diagnosis of unusual-looking, heterogeneous lymphoid proliferations dominated by atypical small or medium-sized lymphoid cells, particularly in young patients.

AB - BACKGROUND: Small cell variant of anaplastic large cell lymphoma (ALCL) is a rare and still underrecognized variant of ALCL. In contrast to the classic type of ALCL, which is sometimes mistaken for carcinoma or sarcoma, the small cell variant may be misdiagnosed as a reactive lesion without a high index of suspicion. CASE: We present a case of small cell variant of ALCL occurring in a 14-year-old female. It posed great difficulty in the fine needle aspiration (FNA) diagnosis due to the rarity of large, atypical cells. A subsequent lymph node biopsy demonstrated the typical histologic and immunophenotypic findings of the small cell variant of ALCL. CONCLUSION: This case indicates that small cell variant of ALCL should always be considered in the FNA diagnosis of unusual-looking, heterogeneous lymphoid proliferations dominated by atypical small or medium-sized lymphoid cells, particularly in young patients.

UR - http://www.scopus.com/inward/record.url?scp=1642318466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1642318466&partnerID=8YFLogxK

U2 - 10.1159/000326327

DO - 10.1159/000326327

M3 - Article

VL - 48

SP - 254

EP - 258

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 2

ER -