Abstract
Non-small-cell lung cancer (NSCLC) is an increasing global challenge, especially in low-income countries. Most guidelines for the management of advanced-stage NSCLC have limited effect in countries with resource constraints. Following a systematic literature search, we present an overview of the management of advanced-stage NSCLC in the first-line setting, discuss resources required for systemic therapy, and provide treatment recommendations stratified to four resources levels. Treatment guidelines appropriate for different resource levels offer a realistic approach to management of advanced-stage NSCLC, by recognising the limitations of a particular health-care system. Although there are many barriers to cancer control in low-resource countries, these can be overcome by using measures that are culturally appropriate, economically feasible, and evidence-based. Initiatives include strategic planning, tobacco control, training of health-care workers, access to therapeutic agents, acquisition of information, public education, and alliances with established institutions and international organisations.
Original language | English |
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Pages (from-to) | 1102-1110 |
Number of pages | 9 |
Journal | The Lancet Oncology |
Volume | 10 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2009 Nov |
Bibliographical note
Funding Information:This work was supported by funding to RAS from the National Healthcare Group ( NHG-RISE 0703 ), the Singapore National Research Foundation, and the Ministry of Education under the Research Center of Excellence Programme.
All Science Journal Classification (ASJC) codes
- Oncology