Flexible and Stretchable PEDOT-Embedded Hybrid Substrates for Bioengineering and Sensory Applications

Afsoon Fallahi, Serena Mandla, Thomas Kerr-Phillip, Jungmok Seo, Raquel O. Rodrigues, Yasamin A. Jodat, Roya Samanipour, Mohammad Asif Hussain, Chang Kee Lee, Hojae Bae, Ali Khademhosseini, Jadranka Travas-Sejdic, Su Ryon Shin

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4-ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.

Original languageEnglish
Pages (from-to)729-737
Number of pages9
JournalChemNanoMat
Volume5
Issue number6
DOIs
Publication statusPublished - 2019 Jun

Bibliographical note

Funding Information:
The authors declare no conflict of interests in this work. The authors also acknowledge funding from the National Institutes of Health (EB021857, AR074234, and EB026824) and the Qatar national Research Fund (a part of Qatar Foundation, NPRP9-144-3-021). S.R.S. would like to recognize and thank Brigham and Women's Hospital President Betsy Nabel, MD, and the Reny family, for the Stepping Strong Innovator Award through their generous funding. R.O.R. acknowledges the Ph.D. scholarship SFRH/BD/97658/2013 granted by FCT ? Funda??o para a Ci?ncia e a Tecnologia, and the Fulbright Research Grant 2017 awarded from Fulbright Portugal. Thomas Kerr-Phillips would like to acknowledge the MacDiarmid Institute for Advanced Materials and Nanotechnology for his PhD scholarship. M.A.H. thanks the National Strategic Technologies and Innovation Program of King Abdulaziz City for Science and Technology (KACST), grant number 11-NAN1544-03 for their support and funding.

Publisher Copyright:
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Renewable Energy, Sustainability and the Environment
  • Energy Engineering and Power Technology
  • Materials Chemistry

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