Flexible and Stretchable PEDOT-Embedded Hybrid Substrates for Bioengineering and Sensory Applications

Afsoon Fallahi; Serena Mandla; Thomas Kerr-Phillip; Jungmok Seo; Raquel O. Rodrigues; Yasamin A. Jodat; Roya Samanipour; Mohammad Asif Hussain; Chang Kee Lee; Hojae Bae; Ali Khademhosseini; Jadranka Travas-Sejdic; Su Ryon Shin

doi:10.1002/cnma.201900146

Flexible and Stretchable PEDOT-Embedded Hybrid Substrates for Bioengineering and Sensory Applications

Afsoon Fallahi, Serena Mandla, Thomas Kerr-Phillip, Jungmok Seo, Raquel O. Rodrigues, Yasamin A. Jodat, Roya Samanipour, Mohammad Asif Hussain, Chang Kee Lee, Hojae Bae, Ali Khademhosseini, Jadranka Travas-Sejdic, Su Ryon Shin

Department of Electrical and Electronic Engineering

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4-ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.

Original language	English
Pages (from-to)	729-737
Number of pages	9
Journal	ChemNanoMat
Volume	5
Issue number	6
DOIs	https://doi.org/10.1002/cnma.201900146
Publication status	Published - 2019 Jun

Bibliographical note

Funding Information:
The authors declare no conflict of interests in this work. The authors also acknowledge funding from the National Institutes of Health (EB021857, AR074234, and EB026824) and the Qatar national Research Fund (a part of Qatar Foundation, NPRP9-144-3-021). S.R.S. would like to recognize and thank Brigham and Women's Hospital President Betsy Nabel, MD, and the Reny family, for the Stepping Strong Innovator Award through their generous funding. R.O.R. acknowledges the Ph.D. scholarship SFRH/BD/97658/2013 granted by FCT – Fundação para a Ciência e a Tecnologia, and the Fulbright Research Grant 2017 awarded from Fulbright Portugal. Thomas Kerr-Phillips would like to acknowledge the MacDiarmid Institute for Advanced Materials and Nanotechnology for his PhD scholarship. M.A.H. thanks the National Strategic Technologies and Innovation Program of King Abdulaziz City for Science and Technology (KACST), grant number 11-NAN1544-03 for their support and funding.

Publisher Copyright:
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

All Science Journal Classification (ASJC) codes

Biomaterials
Renewable Energy, Sustainability and the Environment
Energy Engineering and Power Technology
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/cnma.201900146

Cite this

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title = "Flexible and Stretchable PEDOT-Embedded Hybrid Substrates for Bioengineering and Sensory Applications",

abstract = "Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4-ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.",

author = "Afsoon Fallahi and Serena Mandla and Thomas Kerr-Phillip and Jungmok Seo and Rodrigues, {Raquel O.} and Jodat, {Yasamin A.} and Roya Samanipour and Hussain, {Mohammad Asif} and Lee, {Chang Kee} and Hojae Bae and Ali Khademhosseini and Jadranka Travas-Sejdic and Shin, {Su Ryon}",

note = "Funding Information: The authors declare no conflict of interests in this work. The authors also acknowledge funding from the National Institutes of Health (EB021857, AR074234, and EB026824) and the Qatar national Research Fund (a part of Qatar Foundation, NPRP9-144-3-021). S.R.S. would like to recognize and thank Brigham and Women's Hospital President Betsy Nabel, MD, and the Reny family, for the Stepping Strong Innovator Award through their generous funding. R.O.R. acknowledges the Ph.D. scholarship SFRH/BD/97658/2013 granted by FCT – Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia, and the Fulbright Research Grant 2017 awarded from Fulbright Portugal. Thomas Kerr-Phillips would like to acknowledge the MacDiarmid Institute for Advanced Materials and Nanotechnology for his PhD scholarship. M.A.H. thanks the National Strategic Technologies and Innovation Program of King Abdulaziz City for Science and Technology (KACST), grant number 11-NAN1544-03 for their support and funding. Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2019",

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doi = "10.1002/cnma.201900146",

language = "English",

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AU - Fallahi, Afsoon

AU - Mandla, Serena

AU - Kerr-Phillip, Thomas

AU - Seo, Jungmok

AU - Rodrigues, Raquel O.

AU - Jodat, Yasamin A.

AU - Samanipour, Roya

AU - Hussain, Mohammad Asif

AU - Lee, Chang Kee

AU - Bae, Hojae

AU - Khademhosseini, Ali

AU - Travas-Sejdic, Jadranka

AU - Shin, Su Ryon

N1 - Funding Information: The authors declare no conflict of interests in this work. The authors also acknowledge funding from the National Institutes of Health (EB021857, AR074234, and EB026824) and the Qatar national Research Fund (a part of Qatar Foundation, NPRP9-144-3-021). S.R.S. would like to recognize and thank Brigham and Women's Hospital President Betsy Nabel, MD, and the Reny family, for the Stepping Strong Innovator Award through their generous funding. R.O.R. acknowledges the Ph.D. scholarship SFRH/BD/97658/2013 granted by FCT – Fundação para a Ciência e a Tecnologia, and the Fulbright Research Grant 2017 awarded from Fulbright Portugal. Thomas Kerr-Phillips would like to acknowledge the MacDiarmid Institute for Advanced Materials and Nanotechnology for his PhD scholarship. M.A.H. thanks the National Strategic Technologies and Innovation Program of King Abdulaziz City for Science and Technology (KACST), grant number 11-NAN1544-03 for their support and funding. Publisher Copyright: © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

PY - 2019/6

Y1 - 2019/6

N2 - Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4-ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.

AB - Herein, we introduce a flexible, biocompatible, robust and conductive electrospun fiber mat as a substrate for flexible and stretchable electronic devices for various biomedical applications. To impart the electrospun fiber mats with electrical conductivity, poly(3,4-ethylenedioxythiophene) (PEDOT), a conductive polymer, was interpenetrated into nitrile butadiene rubber (NBR) and poly(ethylene glycol)dimethacrylate (PEGDM) crosslinked electrospun fiber mats. The mats were fabricated with tunable fiber orientation, random and aligned, and displayed elastomeric mechanical properties and high conductivity. In addition, bending the mats caused a reversible change in their resistance. The cytotoxicity studies confirmed that the elastomeric and conductive electrospun fiber mats support cardiac cell growth, and thus are adaptable to a wide range of applications, including tissue engineering, implantable sensors and wearable bioelectronics.

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Flexible and Stretchable PEDOT-Embedded Hybrid Substrates for Bioengineering and Sensory Applications

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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